Category Archives: Population(s)
Prevalence, clinical features, and predictors of adrenal insufficiency in adults with tuberculosis or HIV: A systematic review and meta-analysis
BACKGROUND: Despite the high frequency of adrenal insufficiency (AI) in patients with tuberculosis or HIV, its diagnosis is often missed or delayed resulting in increased mortality. This systematic review and...
Transactivator of transcription (Tat)-induced neuroinflammation as a key pathway in neuronal dysfunction: A scoping review
The activity of HIV-1 and its viral proteins within the central nervous system (CNS) is responsible for a wide array of neuropathological effects, resulting in a spectrum of neurocognitive deficits...
Improving delivery and use of HIV pre-exposure prophylaxis in the US: A systematic review of implementation strategies and adjunctive interventions
Implementation of pre-exposure prophylaxis (PrEP) to prevent HIV transmission is suboptimal in the United States. To date, the literature has focused on identifying determinants of PrEP use, with a lesser...
A systematic review and meta-analysis of HIV transmission risk behaviors, genetic variations, and antiretroviral (ARV) resistance in LGBT populations
Background: Currently, human immunodeficiency virus and acquired immunodeficiency syndrome (HIV/AIDS) has become one of the major health problems worldwide, including Indonesia. East Java is one of the provinces in Indonesia...
Severity of COVID-19 manifestations in HIV patients: A systematic review and meta-analysis
OBJECTIVE: The incidence of coronavirus disease 2019 (COVID-19) pandemic among people living with HIV (PLWH) is experiencing major increases. This demographic is vulnerable due to compromised immune function, but the...
Chest X-ray features of HIV-associated pneumocystis pneumonia (PCP) in adults: A systematic review and meta-analysis
BACKGROUND: The performance of chest x-ray (CXR) features for Pneumocystis pneumonia (PCP) diagnosis has been evaluated in small studies. We conducted a systematic review and meta-analysis to describe CXR changes...
Impact of maternal HIV infection on perinatal outcomes: A systematic review
BACKGROUND: Maternal HIV infection remains a significant global health concern with potential repercussions on perinatal outcomes. Emphasis on early intervention to improve peri- and postnatal outcomes in infected mothers and...
The cost-effectiveness of syphilis screening in pregnant women: A systematic literature review
INTRODUCTION: The cost-effectiveness study of syphilis screening in pregnant women has not been synthesized. This study aimed to synthesize the economic evidence on the cost-effectiveness of syphilis screening in pregnant...
Interventions for integrating behavioral health into HIV settings for US adults: A narrative review of systematic reviews and meta-analyses, 2010–2020
Mental health and substance use disorders can negatively affect physical health, illness management, care access, and quality of life. These behavioral health conditions are prevalent and undertreated among people with...
Comparative efficacy and safety of Pneumocystis jirovecii pneumonia prophylaxis regimens for people living with HIV: A systematic review and network meta-analysis of randomized controlled trials
Background Pneumocystis jirovecii pneumonia (PCP) is a common opportunistic infection among people living with HIV (PWH), particularly among new and untreated cases. Several regimens are available for the prophylaxis of PCP, including...
Biological depiction of lipodystrophy and its associated challenges among HIV AIDS patients: Literature review
Lipodystrophy syndrome is a medical condition characterized by the absence of adipose tissue without any underlying starvation or macromolecule breakdown. In HIV AIDS patients, the use of highly active antiretroviral...