Category Archives: Population(s)

A systematic review with epidemiological update of male genital schistosomiasis (MGS): A call for integrated case management across the health system in sub-Saharan Africa

2018

Male genital schistosomiasis (MGS) is a gender specific manifestation of urogenital schistosomiasis (UGS) first described in 1911 by Madden in Egypt. Today, while affecting millions of men and boys worldwide,...

Prevalence of metabolic syndrome among HIV-positive and HIV-negative populations in sub-Saharan Africa – A systematic review and meta-analysis

2019

BACKGROUND: Metabolic syndrome (MetS) is a constellation of conditions that increase the risk of cardiovascular diseases. It is an emerging concern in sub-Saharan African (SSA) countries, particularly because of an...

Meta-analysis of adherence to highly active antiretroviral therapy in patients with HIV infection in China

2018

With the widespread implementation of antiretroviral therapy in many countries, the HIV/AIDS epidemic has declined. However, little is known about the prevalence of adherence rate to Highly Active Antiretroviral Therapy...

Global and regional molecular epidemiology of HIV-1, 1990-2015: A systematic review, global survey, and trend analysis

2019

BACKGROUND: Global genetic diversity of HIV-1 is a major challenge to the development of HIV vaccines. We aimed to estimate the regional and global distribution of HIV-1 subtypes and recombinants...

The CCR5-Delta32 genetic polymorphism and HIV-1 infection susceptibility: A meta-analysis

2018

The CC chemokine receptor 5 (CCR5) is a chemokine receptor which is widely expressed in several immune cells involved in the inflammatory responses. Previous published studies revealed the relation of...

HIV, depression, and cognitive impairment in the era of effective antiretroviral therapy

2019

PURPOSE OF REVIEW: Mental health disorders, especially depression, are prevalent among people living with HIV (PLWH) and are associated with cognitive impairment (CI) among HIV-uninfected (HIV-) individuals. We conducted a...

Residual or recurrent precancerous lesions after treatment of cervical lesions in HIV-infected women: A systematic review and meta-analysis of treatment failure

2019

Background: Screening and treating premalignant cervical lesions (CIN2+) is an effective way to prevent cervical cancer, and recommendations exist for monitoring of treatment success. Yet, there is no specific recommendation...

Supportive interventions to improve retention on ART in people with HIV in low- and middle-income countries: A systematic review

2018

OBJECTIVES: To determine whether supportive interventions can increase retention in care for patients on antiretroviral therapy (ART) in low- and middle-income countries (LMIC). DESIGN: Systematic review and meta-analysis. METHODS: We...

Content guidance for mobile phones short message service (SMS)-based antiretroviral therapy adherence and appointment reminders: A review of the literature

2018

Mobile phones are increasingly being used to support health activities, including the care and management of people living with HIV/AIDS. Short message service (SMS) has been explored as a means...

Antiretroviral resistance testing in HIV-positive people

2018

BACKGROUND: Resistance to antiretroviral therapy (ART) among people living with human immunodeficiency virus (HIV) compromises treatment effectiveness, often leading to virological failure and mortality. Antiretroviral drug resistance tests may be...

Associations between anxiety and adherence to antiretroviral medications in low- and middle-income countries: A systematic review and meta-analysis

2019

Untreated mental health disorders among people living with HIV (PLHIV) may prevent low- and middle-income countries (LMICs) from achieving the UNAIDS 90-90-90 targets. Anxiety disorders may be associated with decreased...

Socio-structural factors influencing the prevention of mother-to-child transmission of HIV in the democratic republic of the Congo: A systematic review

2019

Introduction The Democratic Republic of the Congo (DRC) had the second-highest mother-to-child HIV transmission rate in Sub-Saharan Africa at 29% in 2013, however the uptake of preventive services for mother-to-child...

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