Category Archives: Population(s)
HIV pre-exposure prophylaxis (PrEP) awareness and acceptability among trans women: a review
Transgender (trans) women are disproportionally burdened by the HIV epidemic due to complex structural, psychosocial and biological factors. HIV pre-exposure prophylaxis (PrEP) is a biomedical prevention approach for people at...
Associations between human leukocyte antigen polymorphisms and hypersensitivity to antiretroviral therapy in patients with human immunodeficiency virus: A meta-analysis
Background Human leukocyte antigen (HLA) alleles are implicated in drug-induced hypersensitivity, including by nevirapine and abacavir. The purpose of this meta-analysis was to evaluate the relationship between HLA polymorphisms and...
Investigation of HIV/AIDS prevalence and associated risk factors among female sex workers from 2010 to 2017: A meta-analysis study
Objectives: Female sex workers (FSW) are highly at risk of HIV, and can potentially transmit the human immunodeficiency virus (HIV) in different societies. Study design: The aims of the present...
Precancerous cervical lesion among HIV-positive women in sub-Saharan Africa: A systematic review and meta-analysis
In sub-Saharan Africa, cervical cancer is an intersecting epidemic with HIV and it is the second most common cause of cancer-related deaths in women. Therefore, this study was aimed to...
Performance of cepheid GeneXpert HIV-1 viral load plasma assay to accurately detect treatment failure: A clinical meta-analysis
BACKGROUND: Coverage of viral load testing remains low with only half of the patients in need having adequate access. Alternative technologies to high throughput centralized machines can be used to...
Cabergoline: A review of its use in the inhibition of lactation for women living with HIV
Introduction: In developed countries, breastfeeding is not recommended for women living with human immunodeficiency virus (WLWH). However, lactation symptoms can be distressing for women who choose not to breastfeed. There is...
Pulmonary hypertension in the global population of adolescents and adults living with HIV: A systematic review and meta-analysis
A systematic review and meta-analysis was conducted to estimate the prevalence of PH in adolescents and adults living with HIV at the global level. PubMed, EMBASE, Web of Science, and...
Adherence to HIV treatment regimens: Systematic literature review and meta-analysis
Background: Antiretroviral therapy (ART), when taken consistently, reduces morbidity and mortality associated with human immunodeficiency virus and viral transmission. Suboptimal treatment adherence is associated with regimen complexity and high tablet burden....
Gestational diabetes mellitus in HIV-infected pregnant women: A systematic review and meta-analysis
BACKGROUND: Impaired glucose metabolism during pregnancy can result in a significant adverse pregnancy-outcomes. Previous studies have reported the contribution of ART to the impaired glucose tolerance and gestational diabetes mellitus...
Case fatality rate and viral aetiologies of acute respiratory tract infections in HIV positive and negative people in Africa: The VARIAFRICA-HIV systematic review and meta-analysis
Background: To set priorities for efficient control of acute respiratory tract infection (ARTI) in Africa, it is necessary to have accurate estimate of its burden, especially among HIV-infected populations. Objectives: To compare...
Comparative efficacy and safety and dolutegravir and lamivudine in treatment naive HIV patients
Objective: Compare the efficacy and safety of the 2-drug antiretroviral therapy regimen dolutegravir + lamivudine (DTG + 3TC) with traditional 3-drug regimens in treatment-naive patients with HIV-1. Design: Data from double-blind, randomized...
