Category Archives: Population(s)

Increasing prevalence of self-reported HIV pre-exposure prophylaxis (PrEP) use in published surveys – A systematic review and meta-analysis

2018

: When combining results from all published surveys, about one in nine global study participants (10.7%) reported ever using PrEP by 2017, a significant increase since U.S. FDA approval in...

Women and HIV/HCV co-infection

2010

Key take-home messages HIV/HCV co-infection increases risk of vertical transmission of both HCV and HIV, and cesarean delivery is recommended. In the studies identified, few gender differences were found to...

Mandatory testing of sex workers for HIV and other sexually transmitted infections

2010

Key take-home messages There is limited research evidence available describing the implications of mandatory HIV/STI testing for sex workers and whether it is effective at reducing the incidence of HIV/STIs....

Rapid HIV testing in correctional facilities

2012

Key take-home messages HIV rates are particularly high in correctional settings. In the U.S., HIV prevalence is five times higher in state and federal correctional systems than in the general...

Gay men’s attitudes to and perceptions of pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP)

2013

Key take-home messages There were fewer studies published on the potential use of non-occupational PEP (nPEP) among men who have sex with men than those on PrEP. Although 47% to...

PTSD among people living with HIV/AIDS

2014

Key take-home messages A high proportion of men and women with HIV have experienced psychological trauma. Although there are no estimates of the prevalence of posttraumatic stress disorder (PTSD) in...

HIV-related stigma in relation to health care professionals in Canada

2015

Key take-home messages There was relatively little literature on the experience of stigma in Canadian health care settings or on the attitudes of Canadian health professionals. In three Canadian studies,...

Blood donor deferral policies for men who have sex with men across high-income countries

2017

Key take-home messages Blood donor deferral policies related to men who have sex with men and transgender people vary significantly across countries. Most counties have relaxed their deferral policies for men who have...

A systematic evaluation of mobile apps to improve the uptake of and adherence to HIV pre-exposure prophylaxis

2018

Background: Pre-exposure prophylaxis, or PrEP, has been shown to be effective at reducing the risk of HIV infection, yet persons at-risk for acquiring HIV exhibit suboptimal uptake of and adherence...

Virologic failure and HIV drug resistance on simplified, dolutegravir-based maintenance therapy: Systematic review and meta-analysis

2018

Background: Dolutegravir-containing maintenance therapy is a promising simplification strategy for virologically suppressed HIV-infected individuals. However, most of the available data to inform this strategy come from small, uncontrolled studies. We...

Assessing the efficacy of lopinavir/ritonavir-based preferred and alternative second-line regimens in HIV-infected patients: A meta-analysis of key evidence to support WHO recommendations

2018

Background: Nucleoside reverse transcriptase inhibitors (NRTIs) and non-NRTIs (NNRTIs) with boosted protease inhibitors are included in standardized first-line and second-line regimens. Recent World Health Organization (WHO) guidelines recommend a boosted...

Do HIV prevention interventions in Asia lead to increase in condom utilization?: A meta-analysis study

2018

This meta-analytic review synthesizes the findings of published independent studies that assessed the effectiveness of HIV prevention interventions in promoting condom usage in Asia. We focused on 20 studies that...

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