Category Archives: Population(s)
Increasing prevalence of self-reported HIV pre-exposure prophylaxis (PrEP) use in published surveys – A systematic review and meta-analysis
: When combining results from all published surveys, about one in nine global study participants (10.7%) reported ever using PrEP by 2017, a significant increase since U.S. FDA approval in...
Blood donor deferral policies for men who have sex with men across high-income countries
Key take-home messages Blood donor deferral policies related to men who have sex with men and transgender people vary significantly across countries. Most counties have relaxed their deferral policies for men who have...
A systematic evaluation of mobile apps to improve the uptake of and adherence to HIV pre-exposure prophylaxis
Background: Pre-exposure prophylaxis, or PrEP, has been shown to be effective at reducing the risk of HIV infection, yet persons at-risk for acquiring HIV exhibit suboptimal uptake of and adherence...
Virologic failure and HIV drug resistance on simplified, dolutegravir-based maintenance therapy: Systematic review and meta-analysis
Background: Dolutegravir-containing maintenance therapy is a promising simplification strategy for virologically suppressed HIV-infected individuals. However, most of the available data to inform this strategy come from small, uncontrolled studies. We...
Assessing the efficacy of lopinavir/ritonavir-based preferred and alternative second-line regimens in HIV-infected patients: A meta-analysis of key evidence to support WHO recommendations
Background: Nucleoside reverse transcriptase inhibitors (NRTIs) and non-NRTIs (NNRTIs) with boosted protease inhibitors are included in standardized first-line and second-line regimens. Recent World Health Organization (WHO) guidelines recommend a boosted...
Do HIV prevention interventions in Asia lead to increase in condom utilization?: A meta-analysis study
This meta-analytic review synthesizes the findings of published independent studies that assessed the effectiveness of HIV prevention interventions in promoting condom usage in Asia. We focused on 20 studies that...
