Category Archives: Population(s)

A meta-analysis of prevalence and moderating factors of malnutrition among people living with HIV across countries

2025

Malnutrition is a critical issue for people living with HIV (PLWH), affecting their immune function, health outcomes, and response to antiretroviral therapy. This meta-analysis assessed the prevalence of malnutrition among...

The Tryptophan-Kynurenine pathway in people living with HIV: A systematic review

2025

Purpose: HIV-1 disrupts the metabolic profile of people living with HIV (PLWH), including the Tryptophan-Kynurenine (Trp-Kyn) pathway, linked to disease outcomes and comorbidities. Despite numerous studies, consensus on key dysregulated metabolites...

Prevalence of common mental disorders and sleep disorder among adolescents and young adults with HIV: A systematic review and meta-analysis

2025

Objective Adolescents and young adults (AYA) with HIV are a population at high risk of experiencing mental issues and sleep disorder. We aim to summarise the global prevalence and risks...

The key design features and effectiveness of social network interventions for HIV testing and linkage services in low- and middle-income countries: A systematic review and meta-analysis

2025

INTRODUCTION: HIV remains a global health challenge with a reported 39 million people living with HIV (PLHIV) in 2022. Sub-Saharan Africa, Asia and the Pacific are home to 82% of...

Measuring mobility in HIV research in sub-Saharan Africa: A scoping review

2025

INTRODUCTION: Mobility-from overnight travel to permanent migration-can reduce service access and increase HIV risk, driving the epidemic in sub-Saharan Africa (SSA). This scoping review described mobility measures used in HIV...

Association between antiretroviral therapy and dental caries in children and adolescents with HIV: A systematic review and meta-analysis

2025

OBJECTIVE: To evaluate the evidenceAÿregarding the association between antiretroviral therapy and dental caries in children and adolescents with HIV. METHODS: Searches were conducted in five international databases (PubMed, Scopus, EMBASE,...

Prevalence of chronic kidney diseases among people living with HIV in Ethiopia: A systematic review and meta-analysis

2025

Background Chronic kidney disease (CKD) is a common condition among people living with HIV worldwide, but it is more common in patients from Africa. Both opportunistic infections and chronic illnesses...

Aetiology of fever of unknown origin in people living with HIV: A systematic review and meta-analysis

2025

Introduction: Fever of unknown origin (FUO) in people living with HIV presents a significant diagnostic challenge due to its broad range of potential aetiologies. Objective: The aims of this study were to...

Health educational interventions for adolescents living with HIV: A scoping review

2025

BACKGROUND: Adolescents living with HIV face unique challenges as they gain greater independence while transitioning into adulthood. They must adjust their self-management activities and take primary responsibility for their health,...

The association between disclosure and antiretroviral therapy among adults living with HIV in China: A systematic review and meta-analysis

2025

Background Antiretroviral therapy (ART) and ART adherence are crucial for preventing HIV transmission and prolonging the lifespan of people living with HIV (PLWH). Serostatus disclosure is a significant factor influencing...

Intimate partner violence among women living with HIV in East Africa: A systematic review and meta-analysis

2025

Background Intimate partner violence (IPV) is a widespread yet often unrecognized problem that affects millions of women worldwide. It is prevalent among marginalized individuals, such as women living with HIV....

Comparison of treatment-emergent resistance-associated mutations and discontinuation due to adverse events among integrase strand transfer inhibitor-based single-tablet regimens and cabotegravir + rilpivirine for the treatment of virologically suppressed people with HIV: A systematic literature review and network meta-analysis

2025

Objective This study evaluated rates of treatment‐emergent resistance‐associated mutations (TE‐RAMs) and discontinuation due to adverse events (DC‐AEs) across integrase strand transfer inhibitor (INSTI)‐based single‐tablet regimens and injectable cabotegravir + rilpivirine...

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