Category Archives: Population(s)
Objective impairments of gait and balance in adults living with HIV-1 infection: A systematic review and meta-analysis of observational studies
BACKGROUND: Gait and balance deficits are reported in adults with HIV infection and are associated with reduced quality of life. Current research suggests an increased fall-incidence in this population, with...
The association between HIV (treatment), pregnancy serum lipid concentrations and pregnancy outcomes: A systematic review
BACKGROUND: Observed adverse effects of antiretroviral therapy (ART) on the lipid profile could be of significance in pregnancy. This systematic review aims to summarize studies that investigated the association between...
Anogenital warts and other HPV-associated anogenital lesions in the HIV-positive patient: A systematic review and meta-analysis of the efficacy and safety of interventions assessed in controlled clinical trials
OBJECTIVES: Anogenital warts (AGW, condylomata acuminata) and intraepithelial neoplasia (IEN) do not only impact health and social well-being, they are also associated with considerable costs for the healthcare systems. Immunocompromised...
A review of the efficacy and safety of genvoya(R) (elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide) in the management of HIV-1 infection
INTRODUCTION: This review evaluates the efficacy and safety of Genvoya(R) (elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide [EVG/c/TAF/FTC]), a single-tablet regimen used for the management of HIV-1 infection. Phase II and...
Dropout from physical activity interventions in people living with HIV: A systematic review and meta-analysis
Physical activity (PA) interventions have been shown to improve the health of people living with HIV (PLWH), yet treatment dropout poses an important challenge. We conducted a meta-analysis to investigate...
Female and younger subjects have lower adherence in PrEP trials: A meta-analysis with implications for the uptake of PrEP service to prevent HIV
OBJECTIVE: To estimate the medicine-taking compliance (MTC) level, explore its facilitators and barriers, and quantify the association between MTC level and pre-exposure prophylaxis (PrEP) protective efficacy in individuals at risk...
Integration of sexually transmitted infection (STI) services into HIV care and treatment services for women living with HIV: A systematic review
OBJECTIVE: To review and critically appraise the existing evidence on integration of sexually transmitted infection (STI) services into HIV care and treatment services for women living with HIV. DESIGN: Systematic...
HIV screening in pregnant women: A systematic review of cost-effectiveness studies
INTRODUCTION: Vertical transmission represents the major route of HIV infection for children. However, the preventive interventions available are extremely effective. This review summarizes evidence regarding the cost-effectiveness of mother-to-child-transmission preventive...
Performance of point-of-care CD4 testing technologies in resource-constrained settings: A systematic review and meta-analysis
BACKGROUND: Point-of-care (POC) CD4 testing increases patient accessibility to assessment of antiretroviral therapy eligibility. This review evaluates field performance in low and middle-income countries (LMICs) of currently available POC CD4...
