Category Archives: Population(s)

Sexually transmitted infection prevalence and testing coverage among people who inject drugs: A systematic review

2025

Background: Individual- and structural-level factors place people who inject drugs at excess risk of sexually transmitted infections (STI). We reviewed existing evidence on STI prevalence and testing coverage among this...

Are cannabis-based medicines a useful treatment for neuropathic pain? A systematic review

2025

Neuropathic pain is a chronic disorder that arises from damaged or malfunctioning nerves. Hypersensitivity to stimuli, also known as hyperalgesia, can cause a person to experience pain from non-painful stimuli,...

Use of self-test to increase HIV testing among men who have sex with men and transgender women—Overview of systematic reviews

2025

ABSTRACT Human Immunodeficiency Virus (HIV) infection is stigmatizing, especially for key populations, who are disproportionately affected by Sexually Transmitted Infections (STIs). The stigma and discrimination suffered by these groups are...

Sensory neuropathy and associated factors among patients living with human immuno-deficiency virus in Africa: A systematic review and meta-analysis

2025

Introduction Despite high prevalence of sensory neuropathy among individuals living with HIV, there is no comprehensive information regarding variables that determine sensory neuropathy onset among the patients who attended health...

How do migrants living with HIV adhere to the HIV care process in high-income countries? A systematic review

2025

BACKGROUND: In high-income countries (HICs), migrants living with HIV (MLHIV) are more likely than other HIV subpopulations to encounter problems which hamper their adherence to the care process; these include...

HIV post-exposure prophylaxis in community settings and by lay health workers or through task sharing: A systematic review of effectiveness, case studies, values and preferences, and costs

2025

INTRODUCTION: Post-exposure prophylaxis (PEP) for HIV prevention has been inadequately promoted, provided and used. Expanded access and task sharing could increase the HIV prevention impact of PEP, but scientific evidence...

Mental health interventions for young pepole living with HIV/AIDS in sub-Saharan Africa: A systematic review

2025

Introduction: Young people (aged 15-24) living with HIV/AIDS (YPLHIV) in sub-Saharan Africa (SSA) experience higher rates of mental health conditions compared to their uninfected peers. Research and practitioners have expressed...

Effects of test-and-treat versus preexposure prophylaxis on elimination of HIV transmission: Analysis of 24 HIV prevention trials

2025

INTRODUCTION: In 2023, 28.8 million (72%) of 39.9 million people with HIV (PWH) worldwide were on treatment with viral suppression, while 11.1 million (28%) people had viraemia with the risk...

Descriptions of risks and benefits of HIV vaccine trials in low-and middle-income countries (LMICs): An integrative review

2025

Human immunodeficiency virus (HIV) vaccine trials are needed in efforts to prevent infection and acquired immunodeficiency syndrome (AIDS). Like other types of research, HIV vaccine trials present benefits and risks...

Mapping the gut microbiota composition in the context of Raltegravir, dolutegravir, and bictegravir—A scoping review

2025

(1) Background: Second-generation integrase strand transfer inhibitors (INSTIs) are now the preferred first-line therapies for human immunodeficiency virus (HIV). However, concerns regarding their side effects, such as weight gain and...

Association between baseline HIV-1 DNA levels and clinical outcomes in people living with HIV: A meta-analysis of cohort studies

2025

This systematic review and meta-analysis evaluated the effect of digital communication tools (e.g., text message reminders) on improving daily oral HIV pre-exposure prophylaxis (PrEP) adherence. Searching PubMed, Embase, Web of...

Analysis of the effect of the COVID-19 pandemic on syphilis in susceptible populations: Me who have sex with men, people living with HIV, and patients with gestational and congenital syphilis—A narrative review

2025

The COVID-19 pandemic triggered a public health crisis that significantly impacted sexually transmitted infections (STIs), particularly syphilis. However, data on syphilis incidence during the pandemic remains inconsistent globally. Key groups...

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