Category Archives: Population(s)

Sensory neuropathy and associated factors among patients living with human immuno-deficiency virus in Africa: A systematic review and meta-analysis

2025

Introduction Despite high prevalence of sensory neuropathy among individuals living with HIV, there is no comprehensive information regarding variables that determine sensory neuropathy onset among the patients who attended health...

How do migrants living with HIV adhere to the HIV care process in high-income countries? A systematic review

2025

BACKGROUND: In high-income countries (HICs), migrants living with HIV (MLHIV) are more likely than other HIV subpopulations to encounter problems which hamper their adherence to the care process; these include...

HIV post-exposure prophylaxis in community settings and by lay health workers or through task sharing: A systematic review of effectiveness, case studies, values and preferences, and costs

2025

INTRODUCTION: Post-exposure prophylaxis (PEP) for HIV prevention has been inadequately promoted, provided and used. Expanded access and task sharing could increase the HIV prevention impact of PEP, but scientific evidence...

User preferences on long-acting pre-exposure prophylaxis for HIV prevention in Eastern and Southern Africa: A scoping review

2025

BACKGROUND: Novel formulations for pre-exposure prophylaxis (PrEP) such as injectables, implants, and intravaginal rings are emerging as long-acting alternatives to daily pills for the prevention of HIV. Eastern and Southern...

A systematic review of T cell epitopes defined from the proteome of human immunodeficiency virus

2025

BACKGROUND: Human immunodeficiency virus (HIV) persists as a formidable and far – reaching threat without a cure. T cells are crucial for antiviral immunity and pathology in HIV patients, with...

Vending machines for reducing harm associated with substance use and use disorders, and co-occurring conditions: A systematic review

2025

Background To stem rising fatal overdoses and other substance use/use disorder (SUD)-related harms, communities are turning to low-barrier harm reduction strategies, such as harm reduction-focused vending machines (VMs) that distribute...

Mapping the gut microbiota composition in the context of Raltegravir, dolutegravir, and bictegravir—A scoping review

2025

(1) Background: Second-generation integrase strand transfer inhibitors (INSTIs) are now the preferred first-line therapies for human immunodeficiency virus (HIV). However, concerns regarding their side effects, such as weight gain and...

Association between baseline HIV-1 DNA levels and clinical outcomes in people living with HIV: A meta-analysis of cohort studies

2025

This systematic review and meta-analysis evaluated the effect of digital communication tools (e.g., text message reminders) on improving daily oral HIV pre-exposure prophylaxis (PrEP) adherence. Searching PubMed, Embase, Web of...

Analysis of the effect of the COVID-19 pandemic on syphilis in susceptible populations: Me who have sex with men, people living with HIV, and patients with gestational and congenital syphilis—A narrative review

2025

The COVID-19 pandemic triggered a public health crisis that significantly impacted sexually transmitted infections (STIs), particularly syphilis. However, data on syphilis incidence during the pandemic remains inconsistent globally. Key groups...

Prevalence of hepatitis B virus infection and its associated factors in Ethiopia: A recent systematic review and meta-analysis

2025

BACKGROUND: Hepatitis B virus (HBV) is one of the most common causes of chronic liver disease and is a growing concern in low-income countries, including Ethiopia. Different studies have been...

Extended-spectrum β-lactamase-producing Enterobacterales among people living with human immunodeficiency virus across the globe: A systematic review and meta-analysis

2025

Background People living with HIV are vulnerable to antibiotic-resistant bacterial infections because of frequent healthcare visits, the consumption of many antimicrobials, and the weakened immune system to fight infections. Our...

Preexposure prophylaxis and intimate partner violence among gay, bisexual, and other men who have sex with men: A global scoping review of the literature

2024

Men who have sex with men (MSM) experience intimate partner violence (IPV) and are at an elevated risk of HIV acquisition. Preexposure prophylaxis (PrEP) is an effective preventative measure against...

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