Category Archives: Population(s)
Alternative administration of antiretroviral therapy in people with HIV unable to swallow: A scoping review
PURPOSE: To review published evidence on alternative administration methods for antiretroviral therapy in patients unable to swallow tablets. METHODS: We conducted a scoping review using PubMed, Web of Science, and...
Factors influencing implementation of point-of-care tests for maternal and newborn screening and diagnosis in low-resource settings: A systematic review
BACKGROUND: Despite the potential of point-of-care (POC) tests to improve maternal and newborn health, implementation in low- and middle-income countries remains inconsistent. POC testing enables rapid, decentralized screening, but barriers...
Effect of donor exclusion criteria on blood safety and volume of donations: A systematic review of modelling studies
Objective To assess the effect of easing bans and deferral policies on blood donation from men who have sex with men on blood safety and volume from modelling studies. Methods We searched...
The gap in integrated pediatric care: A systematic review of family-based weight management for children living with HIV
BACKGROUND: As children living with HIV (CWH) achieve longer life expectancy, they face an emerging ‘double burden’ of infectious and non-communicable diseases, specifically pediatric overweight and obesity (OW/OB). This risk...
Effects of transition from paediatric to adult HIV care on virological outcomes in sub-Saharan Africa: A systematic review and meta-analysis
Background: HIV remains a major global burden, with 2.4 million children and adolescents affected, 84% living in sub-Saharan Africa. As adolescents age, transitioning from paediatric to adult HIV care represents a...
Global coverage of interventions for reduction of injecting drug use-related harm, HIV, viral hepatitis and tuberculosis in prisons and other carceral settings: A systematic review
BACKGROUND: People who are incarcerated experience disproportionately high rates of injecting drug use and infectious disease, including HIV, viral hepatitis and tuberculosis. However, comprehensive global data regarding the availability of...
The vaginal microbiome of pregnant people living with HIV on antiretroviral therapy in the Democratic Republic of Congo: A pilot study and global meta-analysis
Recent studies reveal that a suboptimal vaginal microbiome (VMB), including the enrichment of anaerobic bacteria associated with multiple female genital disorders, is linked to adverse pregnancy and birth outcomes in...
A systematic review and meta-analysis on the association between antiretroviral therapy refill type and viral suppression
To reduce barriers to viral suppression, people living with HIV (PLWH) are placed on multi-month dispensing (MMD)of antiretroviral therapy medication. However, there are concerns about viral rebound following MMD initiation,...
Rapid diagnostic tests, laboratory-based immunoassay and nucleic acid testing strategies for long-acting injectable pre-exposure prophylaxis: A systematic review and meta-analysis
Background Long-acting injectable pre-exposure prophylaxis (LAI-PrEP) is a highly effective biomedical intervention for the prevention of HIV acquisition. There is a strong interest among communities and policymakers for LAI-PrEP scale-up,...
Effectiveness of mobile health (mHealth) interventions on ART adherence among people living with HIV in low- and middle-income countries: A systematic review and meta-analysis
Antiretroviral therapy (ART) is essential for HIV treatment, yet maintaining high adherence remains challenging in resource-limited settings. Mobile health (mHealth) interventions offer a scalable approach to support adherence. This meta-analysis...
Worldwide changes in HIV-related stigma among people living with HIV: A cross-temporal meta-analysis and systematic review
Background: HIV-related stigma among people living with HIV has emerged as a growing public health concern, yet limited longitudinal data are available to characterize its evolution over time. In this study,...
Lived experiences of cancer care for people living with HIV who are treated for anal cancer: A scoping review
OBJECTIVE: This scoping review aims to identify existing evidence on the lived experiences of people living with HIV and treated for anal cancer, and to identify what aspects of health...
