Category Archives: Population(s)
Body composition, hepatic fat, metabolic, and safety outcomes of Tesamorelin, a GHRH analogue, in HIV-associated lipodystrophy: A meta-analysis of randomized controlled trials
Background: HIV-associated lipodystrophy leads to visceral fat accumulation, metabolic complications, body image concerns, medication non-adherence, and increased cardiovascular risks. We thought to assess the effects of Tesamorelin, a synthetic growth hormone-releasing...
Associations between neuroimaging measures and cognitive performance in children, adolescents, and youth living with HIV—A systematic review
PURPOSE OF REVIEW: Neurodevelopmental delays and neuroimaging abnormalities continue to be found in children, adolescents, and youth living with HIV despite the administration of effective combination antiretroviral therapy (cART). However,...
Comparing clinical outcomes of antibiotics for treating Mycobacterium avium complex infection in adults with HIV: A systematic review and network meta-analysis
Background: This study aims to identify the comparative effects of different drug regimens in treating Mycobacterium avium complex (MAC). Methods: PubMed, EMBASE, CENTRAL, and EBSCO Open Dissertations were searched in September 2023....
Barriers to and enablers of adherence to the treatment of active drug-sensitive tuberculosis in people living with HIV: A mixed method systematic review
BACKGROUND: Adherence to tuberculosis (TB) treatment is essential in improving treatment outcomes and reducing TB-related mortality. People living with HIV (PLWH) are at a higher risk of developing and dying...
Incidence of loss to follow-up among East African adults on antiretroviral therapy: A systematic review and meta-analysis
Background Individuals with human immunodeficiency virus receive antiretroviral treatment regardless of their clinical stage or CD4 count. While the “Universal Test and Treat” approach offers benefits, loss to follow-up remains...
An integrative review of PrEP promotion strategies at historically Black colleges and universities to reduce HIV disparities
PURPOSE OF REVIEW: We searched PubMed, CINAHL Plus, Embase, Scopus, Web of Science, and ERIC to identify peer-reviewed studies published between 2015 and 2025 that discussed PrEP at HBCUs. We...
Pre-exposure prophylaxis care engagement among men who have sex with men in the United States during the COVID-19 pandemic: A scoping review
The COVID-19 pandemic substantially impacted the pre-exposure prophylaxis (PrEP) care continuum among men who have sex with men (MSM). While PrEP use during the pandemic has been studied, regional differences...
Integration models for delivering COVID-19 vaccines through HIV services in low-and middle-income countries: A scoping review
BACKGROUND: The Coronavirus Disease 2019 (COVID-19) remains a major global public health issue. People living with HIV (PLHIV) are among the vulnerable groups facing a higher risk of severe outcomes....
Efficacy and safety of bacterial immunostimulants in immunodeficient individuals: A systematic review and meta-analysis
BACKGROUND: Bacterial immunostimulants, such as lysates and trained-immunity vaccines, reduce recurrent respiratory infections and modulate immunity in immunodeficient patients. However, heterogeneity of preparations and limited safety data call for standardized...
Subgingival bacterial microbiota profile of people living with HIV-1 under HAART: A systematic review
Objective This systematic review aimed to assess the available literature on the subgingival bacterial microbiota profiles of PLHIV undergoing HAART. Materials and Methods This research was conducted in accordance with...
HIV pre-exposure prophylaxis among people with criminal justice involvement in the United States: A systematic review
People with criminal justice involvement (PCJI) face a heightened risk of HIV yet remain underserved by prevention strategies such as pre-exposure prophylaxis (PrEP). This systematic review synthesizes current evidence on...
