Category Archives: Population(s)
Optimal anti-retroviral prophylaxis in infants at high-risk of acquiring human immunodeficiency virus: A systematic review
INTRODUCTION: The risk of perinatal HIV infection can be dramatically reduced through maternal antiretroviral therapy (ART) and infant antiretroviral (ARV) postnatal prophylaxis. The 2013 WHO guidelines recommended four to six...
Integrating cardiovascular diseases, hypertension, and diabetes with HIV services: A systematic review
Non-communicable diseases (NCDs), including cardiovascular diseases (CVD), hypertension and diabetes together with HIV infection are among the major public health concerns worldwide. Health services for HIV and NCDs require health...
Systematic review and meta-analysis of the adolescent HIV continuum of care in South Africa: the Cresting Wave
CONTEXT: South Africa has the most HIV infections of any country in the world, yet little is known about the adolescent continuum of care from HIV diagnosis through viral suppression....
Exploring ‘generative mechanisms’ of the antiretroviral adherence club intervention using the realist approach: A scoping review of research-based antiretroviral treatment adherence theories
BACKGROUND: Poor retention in care and non-adherence to antiretroviral therapy (ART) continue to undermine the success of HIV treatment and care programmes across the world. There is a growing recognition...
HIV-free survival at 12-24 months in breastfed infants of HIV-infected women on antiretroviral treatment
OBJECTIVE: To provide estimates of HIV-free survival at 12-24 months in breastfed children by maternal ART (6 months or lifelong) to inform WHO HIV and Infant Feeding guidelines. METHODS: Eighteen...
The potential role of vagus-nerve stimulation in the treatment of HIV-associated depression: A review of literature
Depression is the most common comorbidity and neuropsychiatric complication in HIV. Estimates suggest that the prevalence rate for depression among HIV-infected individuals is three times that of the general population....
The sexual lives of people with disabilities within low- and middle-income countries: A scoping study of studies published in English
BACKGROUND: Although approximately 80% of the global population of people with disabilities reside in low- and middle-income countries (LMICs), very little is known about their sexual lives due to a...
Can the UNAIDS 90-90-90 target be achieved? A systematic analysis of national HIV treatment cascades
BACKGROUND: In 2014, the Joint United Nations Programme on HIV and AIDS (UNAIDS) and partners set the ’90-90-90 targets’; aiming to diagnose 90% of all HIV positive people, provide antiretroviral...
A review of transition experiences in perinatally and behaviourally acquired HIV-1 infection; Same, same but different?
INTRODUCTION: Despite sharing common psychosocial and developmental experiences, adolescents living with perinatally and behaviourally acquired HIV-1 infection are different in terms of timing of HIV infection and developmental stage at...
Risk of colorectal cancer and associated mortality in HIV: A systematic review and meta-analysis
BACKGROUND: As people with HIV live longer, the numbers of colorectal cancer cases are expected to increase. We sought to compare the colorectal cancer incidence and cause-specific mortality among people...
