Category Archives: Population(s)
A systematic review of mediation analysis frameworks in studies examining the determinants of cardiometabolic outcomes in people living with HIV
Introduction Mediation analysis provides a more flexible mechanistic view of the causal relationship between HIV-related factors and cardiometabolic diseases. However, there is limited evidence on how mediation analysis is implemented...
Incidence of adverse drug reactions among HIV patients on antiretroviral drugs in Ethiopia: A systematic review and meta-analysis
Introduction: In recent decades, AIDS–related illnesses have declined due to the widespread use of highly active antiretroviral therapy (HAART). Despite the numerous benefits that HAART provides, it causes significant challenges for...
Prevalence of Mpox vaccine acceptance and hesitancy among people living with HIV: A comprehensive systematic review and meta-analysis
Background Vaccine acceptance among People Living with HIV (PLWH) is crucial for managing and mitigating the spread of infectious diseases, including Mpox. This systematic review and meta-analysis assess the rate...
Growth and body composition of adolescents and young adults with perinatal HIV infection: A systematic review and meta-analysis
Introduction: Approximately 1.3 million pregnancies are exposed to HIV perinatally each year, with transmission rates ranging from 4 to 21%, despite 85% antiretroviral therapy (ART) coverage among pregnant women. While ART...
Efficacy of long-acting cabotegravir plus rilpivirine in viraemic people living with HIV: A systematic review and meta-analysis
BACKGROUND: Long-acting cabotegravir/rilpivirine (LA-CAB/RPV) is currently approved as a switch strategy in people living with HIV virally suppressed on oral antiretroviral therapy. Although small reports on specific, difficult-to-treat populations demonstrated...
What are the risk factors of non-fatal overdose among persons who use opioids? A systematic review and meta-analysis
Introduction: Non-fatal opioid overdose (NFOD) is a concerning public health issue that is a risk factor for subsequent fatal overdose. Methods: This systematic review aimed to evaluate all the previous literature using...
Prevalence and predictors of virological failure among the people living with HIV on antiretroviral treatment in East Africa: Evidence from a systematic review with meta-analysis and meta-regression of published studies from 2016 to 2023
Background: Virological failure (VF) significantly threatens the efficacy of antiretroviral therapy (ART) programs in East Africa. This systematic review and meta-analysis assess the prevalence and predictors of VF among individuals living...
Burden of depression among HIV caregivers in India: A systematic review and meta-analysis
Caregivers of individuals living with HIV face significant mental health challenges, with depression being the most common. Despite global research highlighting this burden, studies specific to the Indian context are...
Evidence on digital HIV self-testing from accuracy to impact: Updated systematic review
BACKGROUND: HIV self-testing has gained momentum following the approval of self-testing methods and novel technological advancements. Digital HIV self-testing involves completing an oral or blood-based HIV self-test with support from...
Comprehensive coronary CT angiography in people living with HIV: A systematic review and meta-analysis
OBJECTIVES: People living with HIV (PLWH) were previously shown to have a higher prevalence of non-calcified coronary plaque with discrepant results for coronary stenosis and any plaque prevalence. This systematic...
