Category Archives: Population(s)

A global review of HIV self-testing: Themes and implications

2017

HIV self-test kits may have the potential to increase testing rates around the globe, and thereby lead to reductions in HIV-related incidence and mortality. However, the effectiveness of these self-test...

Cerebrovascular disease in children with HIV-1 infection

2016

An estimated 3.2 million children worldwide have human immunodeficiency virus (HIV) infection. Antiretroviral therapy (ART) has resulted in prolonged survival, leading to an increase in complications previously recognized in adults....

HCV cure and reinfection among people with HIV/HCV coinfection and people who inject drugs

2017

PURPOSE OF REVIEW: Highly effective, well-tolerated interferon-free direct-acting antivirals (DAA) have revolutionised hepatitis C virus (HCV) therapeutics, with the opportunity for broad treatment scale-up among marginalised or “high-risk” populations, including...

Postnatal HIV transmission in breastfed infants of HIV-infected women on ART: A systematic review and meta-analysis

2017

INTRODUCTION: To systematically review the literature on mother-to-child transmission in breastfed infants whose mothers received antiretroviral therapy and support the process of updating the World Health Organization infant feeding guidelines...

Sedentary behaviour in people living With HIV: A systematic review and meta-analysis

2017

BACKGROUND: Sedentary behaviour is independently associated with an increased risk of poor mental health, developing cardiovascular disease (CVD) and premature mortality. Despite the knowledge that CVD is one of the...

Effectiveness of peer-led interventions to increase HIV testing among men who have sex with men: A systematic review and meta-analysis

2017

HIV testing constitutes a key step along the continuum of HIV care. Men who have sex with men (MSM) have low HIV testing rates and delayed diagnosis, especially in low-resource...

Improving outpatient implementation of preexposure prophylaxis in men who have sex with men

2016

BACKGROUND AND PURPOSE: Preexposure prophylaxis (PrEP) has been shown to decrease the transmission of human immunodeficiency virus (HIV) when used in high-risk populations including men who have sex with men....

New challenges in therapeutic vaccines against HIV infection

2017

INTRODUCTION: There is a growing interest in developing curative strategies for HIV infection. Therapeutic vaccines are one of the most promising approaches. We will review the current knowledge and the...

The benefits of psychosocial interventions for mental health in people living with HIV: A systematic review and meta-analysis

2017

In this systematic review and meta-analysis we investigated the effectiveness of different psychosocial treatments for people living with HIV (PLWH) and mental health problems. Additionally, characteristics that may influence the...

Integrated opioid substitution therapy and HIV care: A qualitative systematic review and synthesis of client and provider experiences

2017

People who use drugs in many contexts have limited access to opioid substitution therapy and HIV care. Service integration is one strategy identified to support increased access. We reviewed and...

The clinical effectiveness of individual behaviour change interventions to reduce risky sexual behaviour after a negative human immunodeficiency virus test in men who have sex with men: Systematic and realist reviews and intervention development

2017

BACKGROUND: Men who have sex with men (MSM) experience significant inequalities in health and well-being. They are the group in the UK at the highest risk of acquiring a human...

A systematic review of patients’ perspectives on the subcutaneous route of medication administration

2016

BACKGROUND: Subcutaneous injections allow for self-administration, but consideration of patients’ perspectives on treatment choice is important to ensure adherence. Previous systematic reviews have been limited in their scope for assessing...

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