Category Archives: Population(s)

Burden of multidrug-resistant bacteria among HIV-positive individuals in Ethiopia: A systematic review and meta-analysis

2024

BACKGROUND: Multidrug-resistant (MDR) bacteria are a significant cause of severe infections, particularly in human immunodeficiency virus (HIV)-positive individuals because of their weakened immunity. Since there was no previous pooled representative...

Adherence and HIV protection thresholds for emtricitabine and tenofovir disoproxil fumarate preexposure prophylaxis among cisgender women: A systematic review

2024

Purpose of review: Adherence-concentration-efficacy benchmarks have not been fully characterized for cisgender women using emtricitabine/tenofovir disoproxil fumarate (FTC/TDF) oral daily pre-exposure prophylaxis (PrEP) for HIV prevention. Recent findings: We conducted a systematic...

Using mHealth technologies for case finding in tuberculosis and other infectious diseases in Africa: Systematic review

2024

BACKGROUND: Mobile health (mHealth) technologies are increasingly used in contact tracing and case finding, enhancing and replacing traditional methods for managing infectious diseases such as Ebola, tuberculosis, COVID-19, and HIV....

Syndemic theory and its use in developing health interventions and programming: A scoping review

2024

PURPOSE OF REVIEW: The central tenet of syndemics theory is that disease interactions are driven by social factors, and that these factors have to be understood in order to reduce...

Self-injury and suicide among people living with HIV/AIDS in China: A systematic review and meta-analysis

2024

Background The prevalence of self-injury and suicide is higher than the general population of people living with HIV/AIDS (PLWHA). However, the results reported in existing studies are highly variable in...

A comparison of active pharmacovigilance strategies used to monitor adverse events to antiviral agents: A systematic review

2024

INTRODUCTION: The safety of antiviral agents in real-world clinical settings is crucial, as pre-marketing studies often do not capture all adverse events (AE). Active pharmacovigilance strategies are essential for detecting...

Prevalence and factors associated with transfusion-transmissible infections (HIV, HBV, HCV and Syphilis) among blood donors in Gabon: Systematic review and meta-analysis

2024

BACKGROUND: Transfusion-transmissible infections (TTIs) remain a major public health problem in countries with limited resources, particularly in Gabon. Complete information on the prevalence in Gabon of the main TTIs among...

A narrative review of novel agents for managing heavily treatment-experienced people living with HIV

2024

Objective: The objective of this review is to compare ibalizumab, fostemsavir, and lenacapavir, present the clinical trials evaluating each agent, and provide guidance on their use in highly-treatment experienced (HTE)...

Identifying effective strategies for improving engagement in HIV prevention and care among transgender persons in the United States: A systematic review

2024

This systematic review synthesized published literature (2000–2023) to identify HIV interventions specifically designed for transgender persons in the United States (PROSPERO registration number: CRD42021256460). The review also summarized strategies for...

Analysis of drug-drug interactions in patients with HIV and metabolic syndrome

2024

BACKGROUND: People with HIV (PWH) are living longer directly related to benefits of highly effective antiretroviral therapy (ART). However, concurrent with improved longevity is the growing prevalence of metabolic comorbidities...

Cervical cancer screening utilization and associated factors among women living with HIV in Ethiopia, 2024: Systematic review and meta-analysis

2024

Background Cervical cancer is a significant global health challenge, with the majority of cases and deaths occurring in low-resource regions like sub-Saharan Africa including Ethiopia. Women living with HIV (WLHIV)...

Delving deeper into the mechanisms fundamental to HIV-associated immunopathology using single-cell sequencing techniques: A scoping review of current literature

2024

Human immunodeficiency virus (HIV) infection has evolved into an established global pandemic over the past four decades; however, despite massive research investment globally, the precise underlying mechanisms which are fundamental...

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