Category Archives: Population(s)
Obstructive lung diseases in HIV: A clinical review and identification of key future research needs
HIV infection has shifted from what was once a disease directly impacting short-term mortality to what is now a chronic illness controllable in the era of effective combination antiretroviral therapy...
Pre-exposure prophylaxis for HIV prevention: Safety concerns
Available evidence supports the efficacy of pre-exposure prophylaxis (PrEP) in decreasing the incidence of human immunodeficiency virus (HIV) infection among high-risk individuals, especially when used in combination with other behavioural...
Returning for HIV test results: A systematic review of barriers and facilitators
This systematic review aims to identify factors that facilitate or hinder the return for HIV test results. Four electronic databases were searched. Two independent reviewers selected eligible publications based on...
Effect of secondary preventive therapy on recurrence of tuberculosis in HIV-infected individuals: A systematic review
Human immunodeficiency virus (HIV)-infected individuals successfully treated for tuberculosis (TB) remain at risk of recurrence of the disease, especially in high TB incidence settings. We performed a systematic review, investigating...
A review of trials investigating efavirenz-induced neuropsychiatric side effects and the implications
Efavirenz is part of the first-line treatment for HIV patients including those in South Africa with approximately 50% experiencing neuropsychiatric side effects. A systematic review of papers reporting neuropsychiatric side...
Cognitive impairment in HIV and HCV co-infected patients: A systematic review and meta-analysis
Cognitive impairment has been well documented in human immunodeficiency virus (HIV) and hepatitis C virus (HCV) mono-infections. However, in the context of HIV/HCV co-infection the research is more limited. The...
A review of HIV prevention studies that use social networking sites: Implications for recruitment, health promotion campaigns, and efficacy trials
This review describes the use of social networking sites (SNS) in the context of primary prevention of HIV. A review was conducted to assess the published literature for HIV interventions...
The association between HIV, antiretroviral therapy and gestational diabetes mellitus: A systematic review and meta-analysis
OBJECTIVES: The widespread, chronic use of antiretroviral therapy (ART) raises questions concerning the metabolic consequences of HIV infection and treatment. Antiretroviral therapy, and specifically protease inhibitors (PIs), has been associated...
Barriers and facilitators to interventions improving retention in HIV care: A qualitative evidence meta-synthesis
Retention in HIV care is vital to the HIV care continuum. The current review aimed to synthesize qualitative research to identify facilitators and barriers to HIV retention in care interventions....
Opening up the HIV epidemic: A review of HIV seropositive status disclosure among people who inject drugs
HIV status disclosure plays a crucial role in reducing risk behaviors of drug and sexual partners and thereby limiting HIV transmission. As people who inject drugs (PWID) bear a significant...
