Category Archives: Population(s)
Efficacy and safety of contemporary dual-drug antiretroviral regimens as first-line treatment or as a simplification strategy: A systematic review and meta-analysis
BACKGROUND: Some guidelines recommended two-drug antiretroviral therapies as alternative regimens to triple therapy in selected patients with the aim of reducing drug burden and toxicity and preserving future treatment options....
Surveillance of HIV transmitted drug resistance in Latin America and the Caribbean: A systematic review and meta-analysis
BACKGROUND: HIV transmitted drug resistance (TDR) remains at moderate level in Latin America and the Caribbean (LAC). However, different epidemiologic scenarios could influence national and sub-regional TDR levels and trends....
Discordant immune response with antiretroviral therapy in HIV-1: A systematic review of clinical outcomes
BACKGROUND: A discordant immune response (DIR) is a failure to satisfactorily increase CD4 counts on ART despite successful virological control. Literature on the clinical effects of DIR has not been...
Can TasP approaches be implemented in correctional settings?: A review of HIV testing and linkage to community HIV treatment programs
High rates of HIV in correctional populations makes evaluation of programs that increase HIV testing in correctional settings and linkage to HIV treatment upon release, and understanding key implementation issues...
Prevalence of oral candidiasis in HIV/AIDS children in highly active antiretroviral therapy era. A literature analysis
SummaryHighly active antiretroviral therapy has decreased the morbidity and mortality related to HIV infection, including oral opportunistic infections. This paper offers an analysis of the scientific literature on the epidemiological...
A meta-analysis assessing all-cause mortality in HIV-exposed uninfected compared to HIV-unexposed uninfected infants and children
OBJECTIVE: Conduct a meta-analysis examining differential all-cause mortality rates between HIV-exposed uninfected infants and children as compared to their HIV-unexposed uninfected counterparts. DESIGN: Meta-analysis summarizing the difference in mortality between...
Examining the associations between HIV-related stigma and health outcomes in people living with HIV/AIDS: A series of meta-analyses
OBJECTIVE: To conduct a systematic review and series of meta-analyses on the association between HIV-related stigma and health among people living with HIV. DATA SOURCES: A structured search was conducted...
Retention of HIV-infected children in the first 12 months of anti-retroviral therapy and predictors of attrition in resource limited settings: A systematic review
Current UNAIDS goals aimed to end the AIDS epidemic set out to ensure that 90% of all people living with HIV know their status, 90% initiate and continue life-long anti-retroviral...
Adolescent sexual and reproductive health services and implications for the provision of voluntary medical male circumcision: Results of a systematic literature review
BACKGROUND: Voluntary medical male circumcision (VMMC) is a critical HIV prevention tool. Since 2007, sub-Saharan African countries with the highest prevalence of HIV have been mobilizing resources to make VMMC...
