Category Archives: Population(s)

Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV-1 drug resistance: An individual-patient- and sequence-level meta-analysis.

2015

BACKGROUND: Regional and subtype-specific mutational patterns of HIV-1 transmitted drug resistance (TDR) are essential for informing first-line antiretroviral (ARV) therapy guidelines and designing diagnostic assays for use in regions where...

Systematic literature review and meta-analysis of renal function in human immunodeficiency virus (HIV)-infected patients treated with Atazanavir (ATV)-based regimens

2015

Some HIV antiretroviral therapies (ART) have been associated with renal toxicities, which become of increasing concern as HIV-infected patients age and develop comorbidities. The objective of this study was to...

Pharmaceutical interventions in antiretroviral therapy: Systematic review and meta-analysis of randomized clinical trials

2015

WHAT IS KNOWN AND OBJECTIVE: High levels of adherence to antiretroviral therapy (ART) are needed to achieve the desired results. Because pharmaceutical care might contribute to improved adherence to treatment,...

Assessment of the impact of cotrimoxazole prophylaxis on key outcomes among HIV-infected adults in low- and middle-income countries: A systematic review

2015

BACKGROUND: Cotrimoxazole (CTX) prophylaxis is among the key interventions provided to HIV-infected individuals in resource-limited settings. We conducted a systematic review of the available evidence. METHODS: MEDLINE, Embase, Global Health,...

Impact of antiretroviral therapy on serum lipoprotein levels and dyslipidemias: A systematic review and meta-analysis

2015

BACKGROUND: Antiretroviral drugs increase biosynthesis and reduce hepatic clearance of serum cholesterol. It is thus important to evaluate the impact of antiretroviral treatment on serum lipoprotein levels and the risk...

Association between the tumor necrosis factor-α-308G/A gene polymorphism and HIV-1 susceptibility: A meta-analysis

2015

The tumor necrosis factor-alpha (TNF-alpha)-308G/A gene polymorphism influences the pathogenesis and evolution of HIV-1 disease. Many studies have evaluated the association between this polymorphism and HIV-1 susceptibility, but the exact...

The impact of HIV-related stigma on the lives of HIV-positive women: An integrated literature review

2016

AIMS AND OBJECTIVES: To critically explore how Human Immunodeficiency Virus-related stigma impacts on the lives of Human Immunodeficiency Virus-positive women through an integrative review of the literature. BACKGROUND: Throughout history...

Oral manifestations of HIV/AIDS in Asia: Systematic review and future research guidelines

2015

OBJECTIVES: The authors have conducted a systematic review of oral manifestations of HIV from studies conducted in Asia to establish the characteristics and prevalence of individual oral manifestations in Asia,...

Tuberculosis treatment non-adherence and lost to follow up among TB patients with or without HIV in developing countries: A systematic review

2015

This systematic review intended to combine factors associated with tuberculosis treatment non-adherence and lost to follow up among TB patients with/without HIV in developing countries. Comprehensive remote electronic databases (MEDLINE,...

Meta-analyses of fertility desires of people living with HIV

2013

BACKGROUND: Literature review has shown that some years back the fertility desires of people living with HIV was low but in the recent years, it was reported as increasing. However,...

Adherence to antiretroviral medications among persons who inject drugs in transitional, low and middle income countries: An international systematic review

2015

Adherence to antiretroviral (ART) medication is vital to reducing morbidity and mortality among HIV positive persons. People who inject drugs (PWID) are at high risk for HIV infection in transitional/low/middle...

A systematic review of the clinical and social epidemiological research among sex workers in Uganda

2015

BACKGROUND: In response to the high burden of disease among sex workers and their position as a population heavily affected by the HIV epidemic, there has been a growing body...

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