Category Archives: Population(s)
Association of HLA-B*5701 genotypes and abacavir-induced hypersensitivity reaction: A systematic review and meta-analysis
OBJECTIVES: This study aimed to systematically review and quantitatively synthesize the association between HLA-B*5701 and abacavir-induced hypersensitivity reaction (ABC-HSR). METHODS: We searched for studies that investigated the association between HLA-B...
Effectiveness of aerobic exercise for adults living with HIV: systematic review and meta-analysis using the Cochrane Collaboration protocol
BACKGROUND: People with HIV are living longer with the health-related consequences of HIV, multi-morbidity, and aging. Exercise is a key strategy that may improve or sustain health for people living...
Detection of lipoarabinomannan (LAM) in urine is an independent predictor of mortality risk in patients receiving treatment for HIV-associated tuberculosis in sub-Saharan Africa: A systematic review and meta-analysis
BACKGROUND: Simple immune capture assays that detect mycobacterial lipoarabinomannan (LAM) antigen in urine are promising new tools for the diagnosis of HIV-associated tuberculosis (HIV-TB). In addition, however, recent prospective cohort...
Disclosure of HIV status to HIV-positive children 12 and under: A systematic cross-national review of implications for health and well-being
WHO estimates that 3.4 million children were living with HIV at the end of 2011, 91% of them in sub-Saharan Africa. Until recently, a largely descriptive literature documented wide variability...
Depression and adherence to antiretroviral therapy in low-, middle- and high-income countries: A systematic review and meta-analysis
We investigated the associations between depressive symptoms and adherence to antiretroviral therapy (ART) among people living with HIV (PLHIV). We searched the PubMed, EMBASE and Cochrane CENTRAL databases for studies...
Nevirapine versus efavirenz for patients co-infected with HIV and tuberculosis: A systematic review and meta-analysis
OBJECTIVES: Antiretroviral therapy (ART) reduces the morbidity and mortality of patients infected with HIV. Standard ART includes either nevirapine or efavirenz, however the efficacy of these drugs is limited in...
What are the benefits and barriers of communicating parental HIV status to seronegative children and the implications for Jamaica? A narrative review of the literature in low/middle income countries
OBJECTIVE: To examine the benefits/barriers for HIV positive parents of communicating their status to seronegative children in low/middle income countries in order to inform policy and practice in Jamaica. METHODS:...
