Category Archives: Population(s)
Basis of selection of first and second line highly active antiretroviral therapy for HIV/AIDS on genetic barrier to resistance: A literature review
Long-term management of HIV/AIDS is at risk of increasing drug resistance1. Booster protease inhibitor (PI) and thymidine analogue-containing regimens have a high genetic barrier to resistance. Non-thymidine-analogue triple nucleoside/nucleotide reverse...
Meta-analysis of studies comparing single and multi-tablet fixed dose combination HIV treatment regimens
Availability of a single source review of once-daily fixed-dose single tablet regimen (STR) and multiple tablet fixed-dose regimen (MTR) would optimally inform healthcare providers and policy makers involved in the...
Prevalence of high-risky behaviors in transmission of HIV among high school and college student MSM in China: A meta-analysis
BACKGROUND: The aim of this study was to investigate the prevalence of high-risky behaviors, such as unprotected anal intercourse (UAI) in the last 6 months, condom using in their last...
Efficacy of inactivated hepatitis a vaccine in HIV-infected patients: A hierarchical Bayesian meta-analysis
Patients with human immunodeficiency virus-1 (HIV) have elevated risk for hepatitis A virus (HAV) coinfection. Sequelae from coinfection include increased risk of liver-related morbidity and mortality. This study synthesizes the...
Trends in HIV prevalence among men who have sex with men in China 2003-09: A systematic review and meta-analysis
BACKGROUND: The year-by-year trend of HIV prevalence among men who have sex with men (MSM) in China is not well documented. METHODS: Published studies on HIV prevalence among MSM in...
A community empowerment approach to the HIV response among sex workers: Effectiveness, challenges, and considerations for implementation and scale-up
A community empowerment-based response to HIV is a process by which sex workers take collective ownership of programmes to achieve the most effective HIV outcomes and address social and structural...
Effective approaches for programming to reduce adolescent vulnerability to HIV infection, HIV risk, and HIV-related morbidity and mortality: A systematic review of systematic reviews
BACKGROUND: In 2012, an estimated 2.1 million adolescents were living with HIV. Though there are effective interventions to prevent and treat HIV infection, adolescents face specific barriers in accessing them....
Cobicistat: A new opportunity in the treatment of HIV disease?
INTRODUCTION: Cobicistat (Cobi), a selective novel CYP3A4 inhibitor, is an orally administered, non-antiretroviral pharmacokinetic enhancer which boosts the plasma levels of several drugs, including HIV-1 protease inhibitors and the integrase...
Differential genotypic evolution of HIV-1 quasispecies in cerebrospinal fluid and plasma: A systematic review
HIV-1 enters the central nervous system by passing the blood-brain barrier during primary infection. Despite the introduction of combination antiretroviral therapy, the prevalence of HIV-associated neurocognitive disorders remains high and...
Brief sexuality communication-a behavioural intervention to advance sexually transmitted infection/HIV prevention: A systematic review
BACKGROUND: Throughout the last decade substantial research has been undertaken to develop evidence-based behaviour change interventions for sexual health promotion. Primary care could provide an opportunistic entry for brief sexual...
Effect of cotrimoxazole prophylaxis on malaria occurrence in HIV-infected patients on antiretroviral therapy in sub-Saharan Africa
OBJECTIVE: To systematically review the evidence on the effect of cotrimoxazole (CTX) on malaria in HIV-positive individuals on antiretroviral therapy (ART). METHODS: Web of Science, PubMed and MEDLINE, EMBASE, Global...
