Category Archives: Population(s)
Efficacy of inactivated hepatitis a vaccine in HIV-infected patients: A hierarchical Bayesian meta-analysis
Patients with human immunodeficiency virus-1 (HIV) have elevated risk for hepatitis A virus (HAV) coinfection. Sequelae from coinfection include increased risk of liver-related morbidity and mortality. This study synthesizes the...
Trends in HIV prevalence among men who have sex with men in China 2003-09: A systematic review and meta-analysis
BACKGROUND: The year-by-year trend of HIV prevalence among men who have sex with men (MSM) in China is not well documented. METHODS: Published studies on HIV prevalence among MSM in...
A community empowerment approach to the HIV response among sex workers: Effectiveness, challenges, and considerations for implementation and scale-up
A community empowerment-based response to HIV is a process by which sex workers take collective ownership of programmes to achieve the most effective HIV outcomes and address social and structural...
Effective approaches for programming to reduce adolescent vulnerability to HIV infection, HIV risk, and HIV-related morbidity and mortality: A systematic review of systematic reviews
BACKGROUND: In 2012, an estimated 2.1 million adolescents were living with HIV. Though there are effective interventions to prevent and treat HIV infection, adolescents face specific barriers in accessing them....
Cobicistat: A new opportunity in the treatment of HIV disease?
INTRODUCTION: Cobicistat (Cobi), a selective novel CYP3A4 inhibitor, is an orally administered, non-antiretroviral pharmacokinetic enhancer which boosts the plasma levels of several drugs, including HIV-1 protease inhibitors and the integrase...
Differential genotypic evolution of HIV-1 quasispecies in cerebrospinal fluid and plasma: A systematic review
HIV-1 enters the central nervous system by passing the blood-brain barrier during primary infection. Despite the introduction of combination antiretroviral therapy, the prevalence of HIV-associated neurocognitive disorders remains high and...
Brief sexuality communication-a behavioural intervention to advance sexually transmitted infection/HIV prevention: A systematic review
BACKGROUND: Throughout the last decade substantial research has been undertaken to develop evidence-based behaviour change interventions for sexual health promotion. Primary care could provide an opportunistic entry for brief sexual...
Effect of cotrimoxazole prophylaxis on malaria occurrence in HIV-infected patients on antiretroviral therapy in sub-Saharan Africa
OBJECTIVE: To systematically review the evidence on the effect of cotrimoxazole (CTX) on malaria in HIV-positive individuals on antiretroviral therapy (ART). METHODS: Web of Science, PubMed and MEDLINE, EMBASE, Global...
Scarcity of protective items against HIV and other bloodborne infections in 13 low- and middle-income countries
OBJECTIVE: To assess protection of surgical healthcare workers against HIV and other bloodborne infections in low- and middle-income countries (LMICs). METHODS: Literature review based on recent studies assessing baseline surgical...
Electronic medication monitoring-informed counseling to improve adherence to combination anti-retroviral therapy and virologic treatment outcomes: A meta-analysis
BACKGROUND: Adherence to combination anti-retroviral therapy for HIV infection is a primary determinant of treatment success, but is often suboptimal. Previous studies have suggested that electronic medication monitoring-informed counseling is...
Circumcision status and risk of HIV acquisition during heterosexual intercourse for both males and females: A meta-analysis
In this study, we evaluated if male circumcision was associated with lower HIV acquisition for HIV (-) males and HIV (-) females during normal sexual behavior. We performed a systematic...
