Category Archives: Population(s)
Antiretroviral therapy in prevention of HIV and TB: Update on current research efforts
There is considerable scientific evidence supporting the use of antiretroviral therapy (ART) in prevention of human immunodeficiency virus (HIV) and tuberculosis (TB) infections. The complex nature of the HIV and...
Sexual risk reduction for HIV-infected persons: A meta-analytic review of “positive prevention” randomized clinical trials
BACKGROUND: Prevention intervention trials have been conducted to reduce risk of sexual transmission among people living with HIV/AIDS (PLWHA), but the findings were inconsistent. We performed a systematic review and...
Clinical trials in sub-Saharan Africa and established standards of care: A systematic review of HIV, tuberculosis, and malaria trials
Context: The minimum standard of care required for participants in clinical trials conducted in resource-poor settings is a matter of controversy; international documents offer contradictory guidance. Objective: To determine whether...
Cost-effectiveness of antenatal HIV-testing: Reviewing its pharmaceutical and methodological aspects
This paper reviews the pharmacoeconomic aspects of antenatal testing for HIV. HIV is a retrovirus which is transmitted among humans through sexual contact, infected blood or blood products (needle sharing...
Prevalence and trend of HIV infection among voluntary blood donors in China since implementation of the Blood Donation Law: A systematic review and meta-analysis
Objective In 1998, the Blood Donation Law was enacted in China in response to the outbreak of HIV endemic in central rural China as a result of unhygienic and commercial...
The VNTR polymorphism of the DC-SIGNR gene and susceptibility to HIV-1 infection: A meta-analysis.
Background: Dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin related (DC-SIGNR) can bind to the human immunodeficiency virus-1 (HIV-1) gp120 envelope glycoprotein and is thus important for the host-pathogen interaction in HIV-1...
Antiretroviral adherence interventions: A review of current literature and ongoing studies
Adherence has proven to be Achilles’ heel of antiretroviral therapy. To achieve the nearly perfect adherence apparently necessary for optimal effects, individuals often require assistance. In this review, we examine...
Maternal infection and risk of preeclampsia: Systematic review and metaanalysis
There are lingering questions regarding the association between maternal infection and preeclampsia. Systematic review and metaanalysis was conducted of observational studies that examined the relationship between maternal infection and preeclampsia....
The impact of HIV treatment on risk behaviour in developing countries: A systematic review
In developing countries, access to antiretroviral therapy (ART) is improving as HIV treatment becomes a greater priority in the global fight against AIDS. While ART has clearly beneficial clinical effects,...
