Category Archives: Population(s)
Socioeconomic status as a risk factor for HIV infection in women in East, Central and Southern Africa: A systematic review
This is a critical, systematic review of the relationship between socioeconomic status (SES) and HIV infection in women in Southern, Central and Eastern Africa. In light of the interest in...
Systematic review exploring time trends in the association between educational attainment and risk of HIV infection in sub-Saharan Africa
OBJECTIVE: To assess the evidence that the association between educational attainment and risk of HIV infection is changing over time in sub-Saharan Africa. DESIGN AND METHODS: Systematic review of published...
Effectiveness of protease inhibitor monotherapy versus combination antiretroviral maintenance therapy: A meta-analysis
BACKGROUND: The unparalleled success of combination antiretroviral therapy (cART) is based on the combination of three drugs from two classes. There is insufficient evidence whether simplification to ritonavir boosted protease...
Nevirapine once daily: Pharmacology, metabolic profile and efficacy data of the new extended-release formulation
Introduction: Nevirapine (NVP), a non-nucleoside reverse transcriptase inhibitor, has been an important component of HIV infection treatment for many years. Currently, twice-a-day dosing is required for the successful application of...
Sex issues in HIV-1-infected persons during highly active antiretroviral therapy: A systematic review
BACKGROUND: Since the introduction of highly active antiretroviral therapy (HAART), morbidity and mortality rates have sharply decreased among HIV-infected patients. Studies of possible differences between men and women in the...
The expanding epidemics of HIV type 1 among men who have sex with men in low- and middle-income countries: Diversity and consistency
Men who have sex with men (MSM) have borne a disproportionate burden of human immunodeficiency virus (HIV) infection and remain a markedly underresourced population globally. To better describe HIV epidemics...
Clinical trials of interactive computerized patient education: Implications for family practice
A systematic review of randomized clinical trials was conducted to evaluate the acceptability and usefulness of computerized patient education interventions. The Columbia Registry, MEDLINE, Health, BIOSIS, and CINAHL bibliographic databases...
A systematic review comparing antiretroviral adherence descriptive and intervention studies conducted in the USA
We examined the extent to which studies aimed at testing interventions to improve antiretroviral adherence have targeted the facilitators of and barriers known to affect adherence. Of the 88 reports...
Interventions for previously untreated patients with AIDS-associated Non-Hodgkin’s Lymphoma
BACKGROUND: Human immunodeficiency virus (HIV) infection is known to be associated with an increased risk of non-Hodgkin’s lymphoma (NHL). The majority of lymphomas (>80%) occurring during immunosuppression are aggressive B-cell...
Pathologising healthy children? A review of the literature exploring the mental health of HIV-affected children in sub-Saharan Africa
This article reviews the expanding body of literature that examines the mental health of HIV-affected children in sub-Saharan Africa. Focusing on primary research across disciplines and methodologies, the review examines...
Antiviral treatment for chronic hepatitis C in patients with human immunodeficiency virus
BACKGROUND: Antiviral treatment for chronic hepatitis C may be less effective if patients are co-infected with human immunodeficiency virus (HIV). OBJECTIVES: To assess the benefits and harms of antiviral treatment...
