Category Archives: Population(s)

Treatment of Kaposi sarcoma in children with HIV-1 infection

2014

Background: Kaposi sarcoma (KS) remains the second most frequently diagnosed HIV-related malignancy (HRM) worldwide and most common HRM in sub-Saharan Africa where HIV is most prevalent and human herpesvirus 8...

HIV, alcohol dependence, and the criminal justice system: A review and call for evidence-based treatment for released prisoners

2011

BACKGROUND: People with both HIV and alcohol use disorders (AUDs) are disproportionately concentrated within the U.S. criminal justice system; approximately one-quarter of all people with HIV cycle through the system...

A review of HIV prevention interventions for juvenile offenders

2010

OBJECTIVE: To conduct a critical review of all HIV prevention intervention studies conducted with adolescents in juvenile justice settings to inform future intervention development. METHOD: PubMed and PsycInfo database searches...

Sexually transmitted infection as a risk factor for homosexual HIV transmission: A systematic review of epidemiological studies

2000

Existing reviews suggest some sexually transmitted infections (STIs) are risk factors in heterosexual HIV transmission. This may not be so in homosexual HIV transmission, about which reviews make no specific...

Health promotion in the city: A structured review of the literature on interventions to prevent heart disease, substance abuse, violence and HIV infection in US metropolitan areas, 1980-1995

2000

To achieve its national public health goals, the US must improve the health of low-income urban populations. To contribute to this process, this study reviewed published reports of health promotion...

Task shifting from doctors to non-doctors for initiation and maintenance of antiretroviral therapy

2014

BACKGROUND: The high levels of healthcare worker shortage is recognised as a severe impediment to increasing patients’ access to antiretroviral therapy. This is particularly of concern where the burden of...

Diagnostic accuracy of the WHO clinical staging system for defining eligibility for ART in sub-Saharan Africa: a systematic review and meta-analysis

2014

Introduction: The World Health Organization (WHO) recommends that HIV-positive adults with CD4 count ≤500 cells/mm(3) initiate antiretroviral therapy (ART). In many countries of sub-Saharan Africa, CD4 count is not widely available...

Analytic review of modeling studies of ARV Based PrEP interventions reveals strong influence of drug-resistance assumptions on the population-level effectiveness

2013

BACKGROUND: Four clinical trials have shown that oral and topical pre-exposure prophylaxis (PrEP) based on tenofovir may be effective in preventing HIV transmission. The expected reduction in HIV transmission and...

Geographical representativeness of published and ongoing randomized controlled trials. The example of: Tobacco consumption and HIV infection

2011

Background: The challenge for evidence-based healthcare is to reduce mortality and the burden of diseases. This study aimed to compare where research is conducted to where research is needed for...

Stable bone density in HAART-treated individuals with HIV: A meta-analysis

2011

Context: Longitudinal studies of bone mineral density (BMD) in HIV have reported conflicting results. Objective: We investigated whether temporal changes in BMD differ by highly active antiretroviral therapy (HAART) status...

Imiquimod for the treatment of genital warts: A quantitative systematic review

2001

OBJECTIVE: To review published randomised controlled trials to assess the benefit and harm of imiquimod in the treatment of external genital warts. DATA SOURCES: MEDLINE (1966 – December 2000), Cochrane...

HIV prevention programs with heterosexuals

2000

Objective: Efficacious HIV prevention programs designed for heterosexual adults were identified. Methods: Thirty-two programs designed with a comparison group and aimed at preventing heterosexual transmission for HIV were identified utilizing...

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