Category Archives: Population(s)
The gap in integrated pediatric care: A systematic review of family-based weight management for children living with HIV
BACKGROUND: As children living with HIV (CWH) achieve longer life expectancy, they face an emerging ‘double burden’ of infectious and non-communicable diseases, specifically pediatric overweight and obesity (OW/OB). This risk...
Effects of transition from paediatric to adult HIV care on virological outcomes in sub-Saharan Africa: A systematic review and meta-analysis
Background: HIV remains a major global burden, with 2.4 million children and adolescents affected, 84% living in sub-Saharan Africa. As adolescents age, transitioning from paediatric to adult HIV care represents a...
Global coverage of interventions for reduction of injecting drug use-related harm, HIV, viral hepatitis and tuberculosis in prisons and other carceral settings: A systematic review
BACKGROUND: People who are incarcerated experience disproportionately high rates of injecting drug use and infectious disease, including HIV, viral hepatitis and tuberculosis. However, comprehensive global data regarding the availability of...
The vaginal microbiome of pregnant people living with HIV on antiretroviral therapy in the Democratic Republic of Congo: A pilot study and global meta-analysis
Recent studies reveal that a suboptimal vaginal microbiome (VMB), including the enrichment of anaerobic bacteria associated with multiple female genital disorders, is linked to adverse pregnancy and birth outcomes in...
A systematic review and meta-analysis on the association between antiretroviral therapy refill type and viral suppression
To reduce barriers to viral suppression, people living with HIV (PLWH) are placed on multi-month dispensing (MMD)of antiretroviral therapy medication. However, there are concerns about viral rebound following MMD initiation,...
Rapid diagnostic tests, laboratory-based immunoassay and nucleic acid testing strategies for long-acting injectable pre-exposure prophylaxis: A systematic review and meta-analysis
Background Long-acting injectable pre-exposure prophylaxis (LAI-PrEP) is a highly effective biomedical intervention for the prevention of HIV acquisition. There is a strong interest among communities and policymakers for LAI-PrEP scale-up,...
PrEP delivery for U.S. adolescents and young adults: A systematic review and narrative synthesis
Despite proven efficacy in preventing human immunodeficiency virus (HIV) transmission, pre-exposure prophylaxis (PrEP) remains underutilized among adolescents and young adults (AYA) in the United States (US). This systematic review and...
Interventions to improve HIV care and treatment outcomes among people with HIV who have substance use disorder or at-risk substance use: A narrative review
Substance use adversely affects engagement in HIV care, adherence to medication, and HIV viral suppression. This review assessed the scope of US interventions designed to promote positive outcomes along the...
Inconsistent condom use and its associated factors among female sex workers in African countries: Systematic review and meta-analysis
Background Inconsistent condom use represents the most proximal behavioral risk factor for acquisition and transmission of sexually transmitted infections, including human immunodeficiency virus. However, certain situations hinder female sex workers...
Global Perspectives on Pre-Exposure Prophylaxis: A Systematic Review and Meta-Analysis of Health Care Providers’ Awareness, Willingness, and Barriers
This systematic review and meta-analysis aimed to assess health care providers’ awareness, willingness, and key barriers in implementing HIV pre-exposure prophylaxis (PrEP). The review followed the Preferred Reporting Items for...
The impact of human immunodeficiency virus coinfection on mpox patients during the 2022 global outbreak: A systematic review and meta-analysis based on comparative observational studies
Background The mpox outbreak in 2022 posed a new challenge to the medical system. We aimed to study the impact of human immunodeficiency virus (HIV) coinfection on mpox patients. Methods This...
Prevalence of oral high-risk HPV and HPV16 infection among people living with HIV: A systematic review and meta-analysis
Objectives: Little is known about the natural history of oral HPV in people living with HIV (PLWH). This systematic review and meta-analysis evaluated oral HPV prevalence among PLWH. Methods: Studies with ≥18-year-old...
