Category Archives: Population(s)
The gut-immune axis in treated HIV infection: From mucosal damage to chronic inflammation and therapeutic opportunities—A clinician-oriented narrative review
Combined antiretroviral therapy (cART) has transformed HIV into a manageable chronic disease. However, people living with HIV (PLWH) experience a 16-year reduction in comorbidity-free life expectancy compared to HIV-negative individuals,...
Perspective of people living with HIV and healthcare workers on the uptake, barriers, and benefits of multimonth dispensing: A qualitative systematic review
INTRODUCTION: Multimonth dispensing (MMD) is a strategy in the HIV care continuum for people living with HIV (PLWH), especially for those who are virally suppressed. With the increase in MMD...
Effects of targeted interventions on HIV testing, knowledge and sexual risk behaviours among long-distance truck drivers: A systematic review and meta-analysis
Objectives We aimed to systematically summarise and quantify the empirical evidence on targeted interventions and their effects on various HIV prevention outcomes for long-distance truck drivers (LDTDs) globally. Design A...
Facilitators and barriers to physical activity in middle-aged and older adult(s) HIV infected persons: A systematic review of qualitative studies
PURPOSE: This study aims to objectively evaluate and synthesize qualitative studies on the facilitators and barriers to PA among middle-aged and older adults living with HIV. METHODS: A systematic search...
Effectiveness of friendship bench in alleviating anxiety and depression symptoms among people living with HIV and high-risk populations: A systematic review and meta-analysis
This systematic review and meta-analysis evaluated the Friendship Bench (FB) intervention’s efficacy in relieving anxiety and depression among people living with HIV (PLHIV) and high-risk populations, explored intervention effect heterogeneity,...
HIV vulnerability among adolescent girls and young women in sub-Saharan Africa: A systematic review of individual social and structural determinants
BACKGROUND: Adolescent girls and young women (AGYW) aged 15 to 24 years continue to bear a disproportionate burden of HIV infections in sub-Saharan Africa. Although substantial research has examined behavioral...
Factors associated with immunological non-response in HIV patients receiving antiretroviral therapy in Southeast Asia: A systematic review
Objective This systematic review summarizes factors associated with immunological non-response (INR) among people with HIV on antiretroviral therapy (ART) in Southeast Asia. Methods We conducted a systematic search of PubMed,...
Integrating smoking cessation into HIV care settings: A systematic review and meta-analysis of effectiveness and the evidence gap in cost-effectiveness
The prevalence of smoking among people living with HIV (PLWH) is higher than in the general population, and PLWH who smoke are at increased risk of both smoking- and HIV-related...
Exercise as a preventive and therapeutic strategy for non-communicable diseases in people living with HIV: Evidence, mechanisms and clinical implications
Objective To synthesise evidence on exercise for preventing and managing non-communicable diseases (NCDs) among HIV clients, emphasising sub-Saharan Africa. Design Narrative review. Data sources Meta-analyses, randomised trials, cohort studies, mechanistic...
Prevalence, genetic diversity, and risk factors of cryptosporidium spp. in HIV/AIDS patients: An updated systematic review and meta-analysis (2017–2025)
Background Cryptosporidium spp. is a major opportunistic pathogens in HIV/AIDS patients, contributing substantially to morbidity and mortality worldwide. Despite advances in HIV/AIDS management, the global burden, genetic diversity, and risk factors...
Integrated care models for HIV, diabetes and hypertension in sub-Saharan Africa: A systematic review of effectiveness, implementation and real-world applicability
Background Sub-Saharan Africa faces a syndemic of HIV and non-communicable diseases (NCDs), particularly diabetes and hypertension. Integrated care models have been promoted to improve service efficiency and patient outcomes; however,...
Hypertension among people living with HIV (PLHIV) compared with people without HIV (PWoH): A systematic review with meta-analysis
Introduction Hypertension is a major cardiovascular risk factor and has increased among people living with HIV. However, evidence on its association with HIV status remains inconsistent. This systematic review aimed...
