Category Archives: Population(s)

Prevalence and risk factors for cytomegalovirus retinitis among people living with HIV in sub-Saharan Africa in the antiretroviral therapy era: A systematic review and meta-analysis

2026

Cytomegalovirus retinitis has remained an alarming and potentially vision-threatening opportunistic disease in the population living with HIV, especially in cases of extreme immunosuppression. Although the introduction of antiretroviral therapy has...

Exploring the potential of cognitive intra-individual variability in HIV care and research in adults with HIV: A concept analysis

2026

Cognitive intraindividual variability (IIV) refers to the variability in one’s ability to sustain consistent cognitive performance. This phenomenon is linked to the emergence of cognitive impairment and dementia. The aim...

Effectiveness of digital health interventions for improving antiretroviral therapy outcomes in people with HIV: Meta-analysis and trial sequential analysis of randomized controlled trials

2026

Background: Digital health interventions (DHIs) are increasingly used to support antiretroviral therapy (ART) management among people living with HIV. However, existing systematic reviews have largely focused on single intervention types or...

Prevalence, genetic diversity, and risk factors of cryptosporidium spp. in HIV/AIDS patients: An updated systematic review and meta-analysis (2017–2025)

2026

Background Cryptosporidium spp. is a major opportunistic pathogens in HIV/AIDS patients, contributing substantially to morbidity and mortality worldwide. Despite advances in HIV/AIDS management, the global burden, genetic diversity, and risk factors...

Integrated care models for HIV, diabetes and hypertension in sub-Saharan Africa: A systematic review of effectiveness, implementation and real-world applicability

2026

Background Sub-Saharan Africa faces a syndemic of HIV and non-communicable diseases (NCDs), particularly diabetes and hypertension. Integrated care models have been promoted to improve service efficiency and patient outcomes; however,...

Hypertension among people living with HIV (PLHIV) compared with people without HIV (PWoH): A systematic review with meta-analysis

2026

Introduction Hypertension is a major cardiovascular risk factor and has increased among people living with HIV. However, evidence on its association with HIV status remains inconsistent. This systematic review aimed...

Temporal shifts in antiretroviral therapy regimens and metabolic outcomes in people living with HIV: A systematic review and meta-analysis

2026

Introduction Antiretroviral therapy (ART) for people living with HIV has led to dramatically reduced mortality and improved life expectancy. This achievement is accompanied by a higher risk for metabolic and...

Socio-cultural and systematic factors influencing fertility desire among women living with HIV: A systematic literature review

2026

Women and girls in Sub-Saharan Africa remain disproportionately affected by HIV. HIV care strategies can significantly reduce the risk of mother-to-child transmission of HIV. Women living with HIV (WLHIV) often...

Condom use and associated factors among people living with HIV/AIDS on anti-retroviral therapy (ART) in Ethiopia: A systematic review and meta-analysis

2026

Condom use remains a crucial preventive measure for individuals undergoing antiretroviral therapy (ART) in the fight against HIV/AIDS. This review and meta-analysis aimed to determine the pooled prevalence of condom...

Prevalence of left ventricular systolic dysfunction in HIV-infected children from sub-Saharan Africa: A systematic review and meta-analysis

2026

Background Left ventricular systolic dysfunction (LVSD) is an emerging non-communicable complication among children living with Human Immunodeficiency Virus (HIV), particularly in Sub-Saharan Africa, where paediatric HIV burden remains high. However,...

Oral health education interventions for people living with HIV: A scoping review of delivery approaches and reported outcomes

2026

Background People living with HIV (PLWH) experience a high burden of oral diseases that can impair daily function and affect adherence to HIV care. Oral health education has the potential...

Exclusive breastfeeding and associated factors among HIV-infected mothers in sub-Saharan African countries: A systematic review and meta-analysis

2026

Introduction The World Health Organization recommends exclusive breastfeeding for the first six months, along with maternal antiretroviral treatment, to reduce the risk of HIV transmission to infants and promote their...

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