Category Archives: Population(s)
Simulation modeling for the design and evaluation of HIV drug resistance interventions: A systematic review of literature
BACKGROUND: The utility of antiretroviral therapy (ART) in the management of human immunodeficiency virus (HIV) is being challenged by growing HIV drug resistance (HIVDR). Although simulation modelling is useful for...
Integration of HIV, Hepatitis B, and C, and sexually transmitted infections services: A scoping review of the benefits and challenges
BACKGROUND: Integrating clinical programs and services is a cost-effective approach that can improve health and system outcomes. This review aimed to provide an overview of the benefits and challenges of...
Interventions to improve access to sexual and reproductive health services for adolescents living with HIV in sub-Saharan Africa: a scoping review
OBJECTIVE: Adolescents living with HIV (ALHIV) face barriers to accessing sexual and reproductive health (SRH) services, negatively affecting their health and quality of life. These challenges are particularly pronounced in...
Prevalence and Risk Factors for Cytomegalovirus Retinitis Among People Living with HIV in Sub-Saharan Africa in the Antiretroviral Therapy Era: A Systematic Review and Meta-Analysis
Cytomegalovirus retinitis has remained an alarming and potentially vision-threatening opportunistic disease in the population living with HIV, especially in cases of extreme immunosuppression. Although the introduction of antiretroviral therapy has...
Integrating smoking cessation into HIV care settings: A systematic review and meta-analysis of effectiveness and the evidence gap in cost-effectiveness
The prevalence of smoking among people living with HIV (PLWH) is higher than in the general population, and PLWH who smoke are at increased risk of both smoking- and HIV-related...
Exercise as a preventive and therapeutic strategy for non-communicable diseases in people living with HIV: Evidence, mechanisms and clinical implications
OBJECTIVE: To synthesise evidence on exercise for preventing and managing non-communicable diseases (NCDs) among HIV clients, emphasising sub-Saharan Africa. DESIGN: Narrative review. DATA SOURCES: Meta-analyses, randomised trials, cohort studies, mechanistic...
Prevalence, Genetic Diversity, and Risk Factors of Cryptosporidium spp. in HIV/AIDS Patients: An Updated Systematic Review and Meta-Analysis (2017-2025)
BACKGROUND: Cryptosporidium spp. is a major opportunistic pathogens in HIV/AIDS patients, contributing substantially to morbidity and mortality worldwide. Despite advances in HIV/AIDS management, the global burden, genetic diversity, and risk...
Integrated Care Models for HIV, Diabetes and Hypertension in Sub-Saharan Africa: A Systematic Review of Effectiveness, Implementation and Real-World Applicability
BACKGROUND: Sub-Saharan Africa faces a syndemic of HIV and non-communicable diseases (NCDs), particularly diabetes and hypertension. Integrated care models have been promoted to improve service efficiency and patient outcomes; however,...
Hypertension among people living with HIV (PLHIV) compared with people without HIV (PWoH): A systematic review with meta-analysis
INTRODUCTION: Hypertension is a major cardiovascular risk factor and has increased among people living with HIV. However, evidence on its association with HIV status remains inconsistent. This systematic review aimed...
Temporal shifts in antiretroviral therapy regimens and metabolic outcomes in people living with HIV: A systematic review and meta-analysis
INTRODUCTION: Antiretroviral therapy (ART) for people living with HIV has led to dramatically reduced mortality and improved life expectancy. This achievement is accompanied by a higher risk for metabolic and...
Socio-cultural and systematic factors influencing fertility desire among women living with HIV: a systematic literature review
Women and girls in Sub-Saharan Africa remain disproportionately affected by HIV. HIV care strategies can significantly reduce the risk of mother-to-child transmission of HIV. Women living with HIV (WLHIV) often...
Condom use and associated factors among people living with HIV/AIDS on Anti-Retroviral Therapy (ART) in Ethiopia: a systematic review and meta-analysis
Condom use remains a crucial preventive measure for individuals undergoing antiretroviral therapy (ART) in the fight against HIV/AIDS. This review and meta-analysis aimed to determine the pooled prevalence of condom...
