Category Archives: Population(s)
Factors influencing implementation of point-of-care tests for maternal and newborn screening and diagnosis in low-resource settings: a systematic review
BACKGROUND: Despite the potential of point-of-care (POC) tests to improve maternal and newborn health, implementation in low- and middle-income countries remains inconsistent. POC testing enables rapid, decentralized screening, but barriers...
Effect of donor exclusion criteria on blood safety and volume of donations: a systematic review of modelling studies
OBJECTIVE: To assess the effect of easing bans and deferral policies on blood donation from men who have sex with men on blood safety and volume from modelling studies. METHODS:...
The Gap in Integrated Pediatric Care: A Systematic Review of Family-Based Weight Management for Children Living with HIV
BACKGROUND: As children living with HIV (CWH) achieve longer life expectancy, they face an emerging ‘double burden’ of infectious and non-communicable diseases, specifically pediatric overweight and obesity (OW/OB). This risk...
Effects of transition from paediatric to adult HIV care on virological outcomes in sub-Saharan Africa: A systematic review and meta-analysis
BACKGROUND: HIV remains a major global burden, with 2.4 million children and adolescents affected, 84% living in sub-Saharan Africa. As adolescents age, transitioning from paediatric to adult HIV care represents...
Global coverage of interventions for reduction of injecting drug use-related harm, HIV, viral hepatitis and tuberculosis in prisons and other carceral settings: A systematic review
BACKGROUND: People who are incarcerated experience disproportionately high rates of injecting drug use and infectious disease, including HIV, viral hepatitis and tuberculosis. However, comprehensive global data regarding the availability of...
The vaginal microbiome of pregnant people living with HIV on antiretroviral therapy in the Democratic Republic of Congo: a pilot study and global meta-analysis
Recent studies reveal that a suboptimal vaginal microbiome (VMB), including the enrichment of anaerobic bacteria associated with multiple female genital disorders, is linked to adverse pregnancy and birth outcomes in...
The Prevalence and Influencing Factors of Frailty Among Middle-Aged and Older Adults With HIV/AIDS From a Global Perspective: A Systematic Review and Meta-Analysis
AIM: Currently, frailty has become a central issue in health management among middle-aged and older people living with HIV/AIDS (PLWHA) worldwide. The objective is to develop targeted strategies to improve...
Effect of omega-3 supplementation on metabolic and inflammatory markers in adults with HIV infection: a systematic review and meta-analysis
BACKGROUND: People living with human immunodeficiency virus (HIV) infection frequently exhibit altered lipid profiles and persistent inflammation that contribute to long-term morbidity. Omega-3 fatty acids are commonly recommended in this...
PrEP Delivery for U.S. Adolescents and Young Adults: A Systematic Review and Narrative Synthesis
Despite proven efficacy in preventing human immunodeficiency virus (HIV) transmission, pre-exposure prophylaxis (PrEP) remains underutilized among adolescents and young adults (AYA) in the United States (US). This systematic review and...
Interventions to Improve HIV Care and Treatment Outcomes Among People with HIV Who Have Substance Use Disorder or At-Risk Substance Use: A Narrative Review
Substance use adversely affects engagement in HIV care, adherence to medication, and HIV viral suppression. This review assessed the scope of US interventions designed to promote positive outcomes along the...
Inconsistent condom use and its associated factors among female sex workers in African countries: Systematic review and meta-analysis
BACKGROUND: Inconsistent condom use represents the most proximal behavioral risk factor for acquisition and transmission of sexually transmitted infections, including human immunodeficiency virus. However, certain situations hinder female sex workers...
Global Perspectives on Pre-Exposure Prophylaxis: A Systematic Review and Meta-Analysis of Health Care Providers’ Awareness, Willingness, and Barriers
This systematic review and meta-analysis aimed to assess health care providers’ awareness, willingness, and key barriers in implementing HIV pre-exposure prophylaxis (PrEP). The review followed the Preferred Reporting Items for...
