Category Archives: Population(s)

The magnitude and patterns of acquired drug resistanace mutations and circulating HIV-1 subtypes in HIV patients in Tanzania, a systematic review and meta-analysis

2025

The emergence and spread of HIV drug resistance mutations (DRMs) pose a threat to current and future treatment options. To inform policy, this review aimed to determine the magnitude and...

Prevalence of low-level viremia and related influencing factors among people living with HIV in China: A systematic review and meta-analysis

2025

Introduction The promotion and application of ART have significantly reduced the mortality rate of AIDS patients in China, but the problem of LLV that follows cannot be ignored. LLV is...

Effects of Moringa oleifera supplementation on immune and nutritional biomarkers in adults living with HIV: A systematic review and meta-analysis

2025

BACKGROUND: Moringa oleifera (MO) is widely used as an adjunctive therapy for individuals living with HIV (PLWH) due to its nutritional and immune-modulating properties. OBJECTIVE: To systematically evaluate the effects...

Effectiveness of conditional cash transfers for uptake and retention in HIV prevention of mother-to-child transmission services in low- and middle-income countries: A systematic review and meta-analysis

2025

OBJECTIVE: The objective of this systematic review was to synthesize the best available evidence on the effectiveness of conditional cash transfers for the uptake and retention in prevention of mother-to-child...

Determinants of HIV related mortality in African children on antiretroviral therapy: Clinical and immunological insights from a systematic review and meta-analysis

2025

BACKGROUND: The HIV epidemic in Africa is still a serious public health concern, particularly for children who are more vulnerable to its negative consequences. Various studies carried out in different...

Characterization and risk stratification of coronary artery disease in people living with HIV: A global systematic review

2025

Background Coronary artery disease (CAD) is a leading cause of mortality among people living with HIV (PLWH). Risk stratification remains inconsistent due to geographic disparities, ART-related metabolic effects, and overreliance...

Global and regional molecular epidemiology of HIV-1 among men who have sex with men: A systematic review and meta-analysis

2025

Objectives The diversity of HIV-1 genotypes among Men who have sex with men (MSM) globally has changed considerably. The purpose of this study to assess the global prevalence of HIV-1...

Motivations, facilitators, and barriers of donation-based interventions in HIV and sexually transmitted infection research: A systematic review

2025

IMPORTANCE: Donation-based prosocial interventions involve someone receiving a free health service and then distributing or donating to support health services for others; examples within the HIV and sexually transmitted infection...

Access and utilization of HIV/STI testing services among men who have sex with men during the COVID-19 pandemic: A systematic review

2025

Background: Men who have sex with men (MSM) continue to bear the disproportionate burden of HIV and other sexually transmitted infections (STIs). The public health response to the COVID-19 pandemic...

Maternal HIV infection and antiretroviral therapy in pregnancy: Implications for vertical transmission, fetal safety, and long-term infant outcomes

2025

HIV mother-to-child transmission (MTCT) continues to pose a significant public health challenge, especially in regions with limited resources, although the worldwide distribution of antiretroviral therapy (ART) has drastically lowered the...

The outcomes of cryptococcal disease in HIV-positive individuals following COVID-19 infection: A systematic review and meta-analysis

2025

Background: Cryptococcal disease is considered a major cause of morbidity in individuals with HIV in resource-limited settings. The long-term effects of COVID-19 and cryptococcal coinfection among people living with HIV (PLWHIV)...

Effectiveness of tuberculosis preventive treatment on disease incidence among people living with HIV/AIDS: A systematic review and meta-analysis

2025

Background Clinical trials have shown the protective efficacy of tuberculosis preventive treatment (TPT) for averting disease and death from tuberculosis among people living with HIV/AIDS (PLHIV). TPT has been recommended...

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