Category Archives: Population(s)
Risk factors for multidrug resistant tuberculosis in Europe: A systematic review
BACKGROUND: The resurgence of tuberculosis (TB) in western countries has been attributed to the HIV epidemic, immigration, and drug resistance. Multidrug resistant tuberculosis (MDR-TB) is caused by the transmission of...
Moderators of the relationship between internalized homophobia and risky sexual behavior in men who have sex with men: A meta-analysis
Research on internalized homophobia (IH) has consistently linked it to both mental and physical health outcomes, while research on its relationships with other variables has been inconsistent. Some research and...
Psychosocial interventions for the reduction of injection and sexual risk behaviour for preventing HIV in drug users
BACKGROUND: Drug users (including both injection drug users and crack cocaine users), are at high levels of risk for contracting HIV. Therefore it is important to reduce the injection and/or...
The impact of Prevention of Mother to Child Transmission (PMTCT) programmes on maternal health care in resource-poor settings: Looking beyond the PMTCT programme – a systematic review
BACKGROUND: There is increasing debate about the impact of scaled-up HIV/AIDS programmes on fragile healthcare systems in low-income countries. OBJECTIVES: To contribute to the understanding of the relation between HIV/AIDS...
Abstinence-plus programs for HIV infection prevention in high-income countries
BACKGROUND: Abstinence-plus interventions promote sexual abstinence as the best means of preventing acquisition of HIV, but also encourage safer-sex strategies (eg condom use) for sexually active participants. OBJECTIVES: To assess...
Behavioral interventions to reduce risk for sexual transmission of HIV among men who have sex with men
BACKGROUND: Men who have sex with men (MSM) remain at great risk for HIV infection. Program planners and policy makers need descriptions of interventions and quantitative estimates of intervention effects...
Meta-analysis: IL-28B genotype and sustained viral clearance in HCV genotype 1 patients
Background Polymorphisms in the IL-28B region are a strong predictor of sustained virologic response (SVR) in individual studies of HCV genotype 1 patients receiving peginterferon (pegIFN) and ribavirin. Aim To...
Treatment of acute cryptococcal meningitis in HIV infected adults, with an emphasis on resource-limited settings
BACKGROUND: Despite the advent and increasingly wide availability of antiretroviral therapy, cryptococcal meningitis (CM) remains a significant cause of mortality and morbidity amongst individuals with HIV infection in resource-limited settings....
How much ritonavir is needed to boost protease inhibitors? Systematic review of 17 dose-ranging pharmacokinetic trials
BACKGROUND: Ritonavir has been evaluated at boosting doses of 50–800 mg daily with seven protease inhibitors: amprenavir, atazanavir, darunavir, indinavir, lopinavir,saquinavir and tipranavir. Minimizing the boosting dose of ritonavir could...
