Category Archives: Population(s)
Estimating the effect of maternal viral load on perinatal and postnatal HIV transmission: A systematic review and meta-analysis
Background Although a growing body of evidence supports zero risk of sexual HIV transmission from a person with sustained virological suppression, known as U=U (undetectable equals untransmittable), data have been...
The diagnostic significance of the C-reactive protein (CRP) in HIV/TB coinfection: A systematic review and meta-analysis
Background Drug-resistant Mycobacterium tuberculosis strains have challenged efforts to combat tuberculosis (TB), a major global killer. C-reactive protein (CRP) shows promise as a biomarker for TB screening, particularly in HIV-positive...
Evaluating predictive performance, validity, and applicability of machine learning models for predicting HIV treatment interruption: A systematic review
Background HIV treatment interruption remains a significant barrier to achieving global HIV/AIDS control goals. Machine learning (ML) models offer potential for predicting treatment interruption by leveraging large clinical data. Understanding...
HIV infection and antiretroviral therapy impair liver function in people living with HIV: Systematic review and meta-analysis
Background: The use of antiretroviral therapy (ART) has improved the lives of people living with HIV (PLWH). However, its use is associated with secondary complications, notably hepatotoxicity. This systematic review and...
Prevalence of and risk factors for suicidal ideation among perinatal women with HIV infection: A systematic review, meta-analysis, and meta-regression
Background The prevalence of suicidal ideation (SI) among HIV-positive pregnant women is a complex issue influenced by multiple risk factors. By addressing these risk factors and focusing on vulnerable regions,...
Worldwide epidemiology of Cyclospora cayetanensis in HIV/AIDS patients: A systematic review and meta-analysis
BACKGROUND: Cyclospora cayetanensis is a coccidian protozoan parasite belonging to the phylum Apicomplexa. This systematic review and meta-analysis aimed to assess the prevalence and risk factors of C. cayetanensis in...
HIV, hepatitis, and syphilis self-testing among adolescents and young adults: A systematic review and meta-analysis
Background: Adolescents and young adults (AYA) make up a significant share of the world’s burden of HIV and other sexually transmitted infections (STI). Self-testing can increase testing coverage and strengthen the...
Meta-analysis of TB & HIV co-infection mortality rate in sub-Saharan African children, youth, and adolescents
Background Despite the effectiveness of antiretroviral treatment (ART) in reducing morbidity and mortality, children and adolescents with co-infections face an elevated risk of death due to their young age and...
Undetectable = Untransmittable: A cross-population systematic review and meta-analysis on awareness and acceptance
The Undetectable = Untransmittable (U=U) message is a cornerstone of HIV-related public health communication, yet global levels of awareness and acceptance remain unclear across key populations. This study aimed to...
Growth patterns of HIV-exposed and -unexposed infants in African countries: A systematic review and meta-analysis
Background/Objectives: The purpose of this study is to understand the prevalence and odds of poor growth patterns among HIV-exposed but uninfected (HEU) versus HIV-unexposed (HUU) infants in the era of antiretroviral...
