Category Archives: Population(s)

Dynamics of hope in adults living with HIV/AIDS: A substantive theory

2005

AIM: The aim of this paper was to discuss a substantive theory on the dynamics of hope in adults living with the human immunodeficiency virus/acquired immune deficiency syndrome. BACKGROUND: Existing...

HIV prevention interventions in adolescent girls: What is the state of the science?

2004

BACKGROUND AND PURPOSE: Adolescent girls now represent one of the fastest growing groups of persons infected with HIV. A systematic review was undertaken to identify and critique the most scientifically...

Association between protease inhibitor use and increased cardiovascular risk in patients infected with human immunodeficiency virus: A systematic review

2003

Some studies have shown that currently available protease inhibitors (PIs) are associated with an increased risk of cardiovascular disease. We have systematically reviewed the published literature and conference abstracts for...

The cost-effectiveness of preventing mother-to-child transmission of HIV in low- and middle-income countries: Systematic review

2011

Background: Although highly effective prevention interventions exist, the epidemic of paediatric HIV continues to challenge control efforts in resource-limited settings. We reviewed the cost-effectiveness of interventions to prevent mother-to-child transmission...

Effect of CCR5-32 heterozygosity on HIV-1 susceptibility: A meta-analysis

2012

So far, many studies have investigated the distribution of CCR5 genotype between HIV-1 infected patients and uninfected people. However, no definite results have been put forward about whether heterozygosity for...

Health-related quality of life assessment in adult haemophilia patients: A systematic review and evaluation of instruments

2003

The objective of this study was to review and evaluate the performance of health-related quality of life (HRQL) and other health status measures used in studies of adult haemophilia and...

Systematic review of the safety of trimethoprim-sulfamethoxazole for prophylaxis in HIV-infected pregnant women: Implications for resource-limited settings

2006

Daily prophylaxis with trimethoprim-sulfamethoxazole (TMP-SMZ) significantly decreases morbidity and mortality among people living with HIV. Some clinicians are reluctant to use TMP-SMZ in pregnant and breastfeeding HIV-infected women because of...

Older persons’ exclusion from sexually transmitted disease risk-reduction clinical trials

2007

BACKGROUND: The incidence of HIV and AIDS is growing faster among individuals 50 and older compared to those under 40. Although the majority of clinical trials aimed at treating diseases...

Interventions to reduce risky sexual behaviour for preventing HIV infection in workers in occupational settings

2011

Background: HIV in the workforce has a negative impact on economic growth and development of affected countries. The workplace provides an important avenue to prevent HIV by providing easy access...

A review of the efficacy and outcomes studies of currently approved chemotherapy treatments for advanced AIDS-Kaposi’s sarcoma

2011

Background: Acquired Immune Deficiency Syndrome (AIDS) – related Kaposi’s sarcoma (KS) is a rare aggressive tumor. The benefits of drug therapy are established by clinical trials but it has been...

HIV incidence estimation using the BED capture enzyme immunoassay: Systematic review and sensitivity analysis

2010

BACKGROUND: HIV incidence estimates are essential for understanding the evolution of the HIV epidemic and the impact of interventions. Tests for recent HIV infection allow incidence estimation based on a...

The effectiveness of condoms in reducing heterosexual transmission of HIV

1999

CONTEXT: It is not established whether the condom is as effective at preventing heterosexual transmission of HIV as it is for preventing conception. An overall estimate of condom effectiveness for...

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