Category Archives: Population(s)

Raltegravir: the first HIV integrase inhibitor

2008

BACKGROUND: The availability of new classes of antiretroviral drugs has made it possible for HIV-infected individuals who are highly treatment experienced to achieve the goals of immunologic recovery and virologic...

Standard care quality determines treatment outcomes in control groups of HAART-adherence intervention studies: Implications for the interpretation and comparison of intervention effects.

2009

Objective: Clinical trials of behavioral interventions seek to enhance evidence-based health care. However, in case the quality of standard care provided to control conditions varies between studies and affects outcomes,...

Induction effects of ritonavir: Implications for drug interactions

2008

OBJECTIVE: To review the literature on the induction effects of ritonavir on the cytochrome P450 enzyme system and glucuronyl transferase and identify resultant established and potential drug interactions. DATA SOURCES:...

Interventions for squamous cell carcinoma of the conjunctiva in HIV-infected individuals

2007

Background: Squamous cell carcinoma of the conjunctiva is a rare, slow-growing tumour of the eye, normally affecting elderly men around 70 years of age. In Africa, however, the disease is...

Complementary AIDS therapies: The good, the bad and the ugly

1997

HIV-infected/AIDS patients seem to frequently use complementary therapies, yet definitive information in this area is difficult to obtain. The aim of this systematic review is therefore to assess the published...

A systematic review of randomized controlled trials of prenatal and postnatal vitamin A supplementation of HIV-infected women

2009

We searched the Cochrane Library, MEDLINE, EMBASE, AIDSearch, and Gateway to assess the effect of prenatal and/or postnatal vitamin A supplementation on the risk of mother-to-child transmission (MTCT) of HIV...

Children facing a family member’s acute illness: A review of intervention studies

2007

BACKGROUND: A review of psycho-educational intervention studies to benefit children adapting to a close (parent, sibling, or grandparent) family member’s serious illness was conducted. OBJECTIVES: To review the literature on...

The efficacy and safety of multivitamin and mineral supplement use to prevent cancer and chronic disease in adults: a systematic review for a National Institutes of Health State-of-the-Science Conference

2006

BACKGROUND: Multivitamin and mineral supplements are the most commonly used dietary supplements in the United States. PURPOSE: To synthesize studies on the efficacy and safety of multivitamin/mineral supplement use in...

Risk of cardiovascular disease from antiretroviral therapy for HIV: A systematic review

2013

BACKGROUND: Recent studies suggest certain antiretroviral therapy (ART) drugs are associated with increases in cardiovascular disease. PURPOSE: We performed a systematic review and meta-analysis to summarize the available evidence, with...

Radiographic features of paediatric pneumocystis pneumonia — A historical perspective

2008

AIM: To determine differences between the plain radiographic features of paediatric pneumocystis pneumonia (PCP) recorded before the emergence of human immunodeficiency virus (HIV) in 1982 and those documented in the...

CD4+ guided antiretroviral treatment interruption in HIV infection: A meta-analysis

2008

The aim of this meta-analysis study was to evaluate the relative risk of death or AIDS-defining events associated to CD4+ guided treatment interruption in patients with chronic HIV infection. A...

Motivational interviewing targeting risk reduction for people with HIV: A systematic review

2012

Due to the co-occurrence of sexual risk behaviors and substance use among HIV-positive individuals, there is often a need for HIV prevention efforts to target multiple behaviors. Motivational Interviewing (MI),...

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