Category Archives: Population(s)
Diagnostic tests in HIV management: A review of clinical and laboratory strategies to monitor HIV-infected individuals in developing countries
We conducted a systematic review on the performance of diagnostic tests for clinical and laboratory monitoring of HIV-infected adults in developing countries. Diagnostic test information collected from computerized databases, bibliographies...
HIV prevention in young people in sub-Saharan Africa: A systematic review
Purpose: To systematically review and update evidence on the effectiveness of youth HIV/AIDS prevention interventions in sub-Saharan Africa (SSA) and to make evidence-based policy recommendations to guide efforts toward meeting...
Mental health service delivery in South Africa from 2000 to 2010: One step forward, one step back
Objectives. To identify progress and challenges in mental healthcare in South Africa, as well as future mental health services research priorities. Method. A systematic review of mental health services research....
The role of coinfections in HIV epidemic trajectory and positive prevention: A systematic review and meta-analysis
OBJECTIVES: Recurrent or persistent coinfections may increase HIV viral load and, consequently, risk of HIV transmission, thus increasing HIV incidence. We evaluated the association between malaria, herpes simplex virus type...
Performance of commercial herpes simplex virus type-2 antibody tests using serum samples from Sub-Saharan Africa: A systematic review and meta-analysis
BACKGROUND: Several commercial type-specific serologic tests are available for herpes simplex virus type 2 (HSV-2). Poor specificity of some tests has been reported on samples from sub-Saharan Africa. METHODS: To...
Effect of sulfadoxine-pyrimethamine resistance on the efficacy of intermittent preventive therapy for malaria control during pregnancy: A systematic review
CONTEXT: In malaria-endemic regions, strategies to control malaria during pregnancy rely on case management of malaria illness and anemia, and preventive measures such as insecticide-treated nets and intermittent preventive therapy...
Predictive value of interferon- release assays for incident active tuberculosis: A systematic review and meta-analysis
Background: We aimed to assess whether interferon- release assays (IGRAs) can predict the development of active tuberculosis and whether the predictive ability of these tests is better than that of...
A review of the virological efficacy of the 4 world health organization-recommended tenofovir-containing regimens for initial HIV therapy
We systematically reviewed studies of the virological efficacy of the 4 new tenofovir (TDF)-containing regimens recommended for initial antiretroviral (ARV) therapy in the 2010 World Health Organization ARV Treatment Guidelines....
Nonnucleoside reverse transcriptase inhibitor resistance and the role of the second-generation agents
OBJECTIVE: To review the current state of nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance, discuss the promising role of second-generation NNRTIs, and provide insight into their clinical utility. DATA SOURCES: Articles...
