Category Archives: Population(s)

Isoniazid preventive therapy in correctional facilities: A systematic review

2012

Tuberculosis (TB) remains a major cause of morbidity and mortality worldwide and the main cause of death in correctional facilities in middle- and low-income countries. Due to the closed environment...

Integrating prevention of mother-to-child HIV transmission programs to improve uptake: A systematic review

2012

Background: We performed a systematic review to assess the effect of integrated perinatal prevention of mother-to-child transmission of HIV interventions compared to non- or partially integrated services on the uptake...

Review and meta-analysis of HIV prevention intervention research for heterosexual adult populations in the United States

2002

A meta-analysis was performed to examine the effects of 14 behavioral and social interventions for heterosexual adults on their adoption of safer sex behaviors or incidence of sexually transmitted diseases...

Use of cidofovir in progressive multifocal leukoencephalopathy

2001

BACKGROUND: Progressive multifocal leukoencephalopathy (PML) is a subacute demyelinating illness caused by the JC virus, a polyomavirus that occurs in 4-5% of HIV-positive patients. Mortality is high, and no useful...

Nonoxynol-9 spermicide for prevention of vaginally acquired HIV and other sexually transmitted infections: Systematic review and meta-analysis of randomised controlled trials including more than 5000 women

2002

We aimed to determine the effectiveness of the vaginally administered spermicide nonoxynol-9 (N-9) among women for the prevention of HIV and other sexually transmitted infections (STIs). We did a systematic...

HIV in the Middle East and North Africa: Priority, culture, and control

2013

OBJECTIVES: This study aimed to assess the priority of HIV/AIDS in the Middle East and North Africa region and compare it with other regions. This review examines the social, cultural...

Discontinuation of Pneumocystis jirovecii pneumonia prophylaxis with CD4 count <200 cells/mul and virologic suppression: A systematic review

2011

Background: HIV viral load (VL) is currently not part of the criteria for Pneumocystis jirovecii pneumonia (PCP) prophylaxis discontinuation, but suppression of plasma viremia with antiretroviral therapy may allow for...

Therapeutic drug monitoring and drug-drug interactions involving antiretroviral drugs

2005

The consensus of current international guidelines for the treatment of HIV infection is that data on therapeutic drug monitoring (TDM) of non-nucleoside reverse transcriptase inhibitors (NNRTIs) and protease inhibitors (Pls)...

Cytotoxic T-lymphocyte responses to canarypox vector-based HIV vaccines in HIV-seronegative individuals: A meta-analysis of published studies

2004

PURPOSE: A successful prophylactic HIV vaccine will probably require neutralizing antibodies and vigorous CTL (CD8+ T-cytotoxic lymphocyte) responses. Canarypox vector-based HIV vaccines (ALVAC-HIV) have been gaining momentum as promising HIV...

The neurology of HIV infection – A review of the literature

2005

BACKGROUND: The nervous system is widely involved in the course of infection with the human immunodeficiency virus (HIV). The manifestation may be a direct effect of the virus, the result...

Linking women who test HIV-positive in pregnancy-related services to long-term HIV care and treatment services: A systematic review

2012

Objectives To quantify attrition between women testing HIV-positive in pregnancy-related services and accessing long-term HIV care and treatment services in low- or middle-income countries and to explore the reasons underlying...

The effect on treatment adherence of administering drugs as fixed-dose combinations versus as separate pills: Systematic review and meta-analysis

2014

Administering drugs as fixed-dose combinations (FDCs) versus the same active drugs administered as separate pills is assumed to enhance treatment adherence. We synthesized evidence from randomized controlled trials (RCTs) about...

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