Category Archives: Population(s)
Interferon-gamma release assays for active pulmonary tuberculosis diagnosis in adults in low- and middle-income countries: systematic review and meta-analysis
BACKGROUND: The diagnostic value of interferon-gamma release assays (IGRAs) for active tuberculosis in low- and middle-income countries is unclear. METHODS: We searched multiple databases for studies published through May 2010...
Head-to-head comparison of accuracy of a rapid point-of-care HIV test with oral versus whole-blood specimens: A systematic review and meta-analysis
BACKGROUND: The focus on prevention strategies aimed at curbing the HIV epidemic is growing, and therefore screening for HIV has again taken centre stage. Our aim was to establish whether...
A systematic review of behavioral and treatment outcome studies among HIV-infected men who have sex with men who abuse crystal methamphetamine
Men who have sex with men (MSM) have the highest incidence of HIV infection in the United States. One of the contributing factors to HIV spread among this group is...
Etravirine as a switching option for patients with HIV RNA suppression: A review of recent trials
Unlike other nonnucleoside reverse transcriptase inhibitors, etravirine is only approved for use in treatment-experienced patients. In the DUET 1 and 2 trials, 1203 highly treatment-experienced patients were randomized to etravirine...
A systematic review of psychological functioning of children exposed to HIV: Using evidence to plan for tomorrow’s HIV needs
Prevention of mother to child transmission of HIV can virtually eliminate paediatric HIV infection. Studies are needed to understand child development outcomes for children exposed to HIV in utero but...
How does the mining industry contribute to sexual and reproductive health in developing countries? A narrative synthesis of current evidence to inform practice
AIMS AND OBJECTIVES: To explore client and provider experiences and related health outcomes of sexual and reproductive health interventions that have been led by or that have involved mining companies....
Infections and inflammatory diseases as risk factors for venous thrombosis. A systematic review
Inflammation and venous thrombosis are intertwined. Only in the recent 15 years clinical epidemiological studies have focussed on inflammatory or infectious diseases as risk factors for venous thrombosis. Although a...
HIV testing in community settings in resource-rich countries: A systematic review of the evidence
OBJECTIVES: Community HIV testing represents an opportunity for diagnosing HIV infection among individuals who may not have contact with health services, especially in hard-to-reach groups. The aim of this review...
Effective approaches to reducing adolescent unprotected sex, pregnancy, and childbearing
In the United States, there exist a multitude of different approaches to reducing adolescent sexual risk-taking, unintended pregnancy, childbearing, and sexually transmitted disease, including HIV. While many of these approaches...
Treatment outcomes from community-based drug resistant tuberculosis treatment programs: A systematic review and meta-analysis
BACKGROUND: There is increasing evidence that community-based treatment of drug resistant tuberculosis (DRTB) is a feasible and cost-effective alternative to centralized, hospital-based care. Although several large programs have reported favourable...
