Category Archives: Population(s)

Does gender bias exist in the use of specialist health care?

2000

OBJECTIVES: To investigate the evidence for the existence of gender bias (defined as care provided independently of clinical need) in the use of specialist services by critically appraising the literature....

Nevirapine or efavirenz combined with two nucleoside reverse transcriptase inhibitors compared to HAART: A meta-analysis of randomized clinical trials

2001

Purpose: A meta-analysis of randomized controlled trials (RCTs) was performed to evaluate effectiveness and tolerability of triple antiretroviral therapy regimens in HIV-infected patients. Method: RCTs including the nonnucleoside reverse transcriptase...

Pneumocystis jirovecii pneumonia in tropical and low and middle income countries: A systematic review and meta-regression

2013

OBJECTIVE: Pneumocystis jirovecii pneumonia (PCP), the commonest opportunistic infection in HIV-infected patients in the developed world, is less commonly described in tropical and low and middle income countries (LMIC). We...

Review of drug interactions with telaprevir and antiretrovirals

2013

HCV infection is a major cause of mortality worldwide. HCV-related deaths also represent a leading cause of mortality in HIV-coinfected individuals. Telaprevir is an NS3/4A protease inhibitor approved for the...

Pharmacologic perspectives for once-daily antiretroviral therapy

2004

OBJECTIVE: To contrast available once-daily antiretroviral agents and combinations of these agents from a clinical pharmacologic viewpoint. DATA SOURCES: Data were extracted from publications and major HIV conference proceedings cited...

Testosterone replacement therapy for bone loss prevention in HIV-infected males

2003

OBJECTIVE: To review the use of testosterone for the prevention of bone loss in men with HIV infection. DATA SOURCES: A MEDLINE search (1966-May 2002) on the use of testosterone...

Cotrimoxazole prophylaxis for opportunistic infections in adults with HIV

2003

BACKGROUND: The prevention and early treatment of infections are the mainstay of the medical management of the majority of people with HIV infection, who live in low income countries without...

HIV risks among injecting drug users in Vietnam: A review of the research evidence

2012

Injecting drug use plays a critical role in the transmission of HIV in Vietnam. This paper provides a comprehensive review of studies on risks of HIV infection among injecting drug...

Antiretroviral therapy in prevention of HIV and TB: Update on current research efforts

2011

There is considerable scientific evidence supporting the use of antiretroviral therapy (ART) in prevention of human immunodeficiency virus (HIV) and tuberculosis (TB) infections. The complex nature of the HIV and...

Sexual risk reduction for HIV-infected persons: A meta-analytic review of “positive prevention” randomized clinical trials

2014

BACKGROUND: Prevention intervention trials have been conducted to reduce risk of sexual transmission among people living with HIV/AIDS (PLWHA), but the findings were inconsistent. We performed a systematic review and...

Clinical trials in sub-Saharan Africa and established standards of care: A systematic review of HIV, tuberculosis, and malaria trials

2004

Context: The minimum standard of care required for participants in clinical trials conducted in resource-poor settings is a matter of controversy; international documents offer contradictory guidance. Objective: To determine whether...

Complementary therapies for the treatment of HIV: In search of the evidence

2005

The use of complementary and alternative medicine (CAM) is widespread. Yet, little is known about the evidence supporting its use in HIV/AIDS. We conducted a systematic review of randomized clinical...

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