Category Archives: Population(s)
Treatment of cryptosporidiosis in immunocompromised individuals: Systematic review and meta-analysis
Cryptosporidium is a common cause of gastroenteritis and is associated with severe life-threatening illness among immunocompromised individuals. This review aimed to assess the efficacy of interventions for the treatment and...
Efficacy of group psychotherapy to reduce depressive symptoms among HIV-infected individuals: A systematic review and meta-analysis
Depressed mood is highly prevalent among HIV-infected individuals. Some but not all studies have found group psychotherapy to be efficacious in this population. We performed a systematic review and meta-analysis...
Post-HAART outcomes in pediatric populations: Comparison of resource-limited and developed countries
CONTEXT: No formal comparison has been made between the pediatric post-highly active antiretroviral therapy (HAART) outcomes of resource-limited and developed countries. OBJECTIVE: To systematically quantify and compare major baseline characteristics...
A systematic review of school-based sexual health interventions to prevent STI/HIV in sub-Saharan Africa
BACKGROUND: The HIV/AIDS epidemic remains of global significance and there is a need to target (a) the adolescent age-groups in which most new infections occur; and (b) sub-Saharan Africa where...
Systematic review and meta-analysis of the diagnostic accuracy of fibrosis marker panels in patients with HIV/hepatitis C coinfection
BACKGROUND: Accurately staging hepatitis C virus (HCV)-related fibrosis is crucial for treatment decisions and prognostication. Our objective was to systematically review studies describing the accuracy of serum marker panels for...
A combination drug of abacavir-lamivudine-zidovudine (Trizivir (R)) for treating HIV infection and AIDS
BACKGROUND: The human immunodeficiency virus (HIV) has become one of the greatest challenges to global public health. In 2007 UNAIDS estimated that 33.2 million people were living with HIV. Currently...
Socio-demographic characteristics and behavioral risk factors of female sex workers in sub-saharan Africa: A systematic review
Sex work remains an important contributor to HIV transmission within early, advanced and regressing epidemics in sub-Saharan Africa, but its social and behavioral underpinnings remain poorly understood, limiting the impact...
Etravirine (TMC-125): The evidence for its place in the treatment of HIV-1 infection
Introduction: Etravirine is a novel nonnucleoside reverse transcriptase inhibitor (NNRTI) specifically designed to suppress the replication of viruses resistant to the three currently approved NNRTIs efavirenz, nevirapine, and delavirdine. Aims:...
Stress management interventions for HIV+ adults: A meta-analysis of randomized controlled trials, 1989 to 2006
Objective: Numerous studies document that stress accelerates disease processes in a variety of diseases including HIV. As a result, investigators have developed and evaluated interventions to reduce stress as a...
