Category Archives: Population(s)

Tesamorelin: A growth hormone-releasing factor analogue for HIV-associated lipodystrophy

2012

OBJECTIVE: To evaluate the efficacy and safety of tesamorelin, a growth hormone releasing factor analogue approved by the Food and Drug Administration in November 2010 for the treatment of lipodystrophy...

Experiences integrating delivery of maternal and child health services with childhood immunization programs: Systematic review update

2012

BACKGROUND: The World Health Organization and the United Nations Children’s Fund promote integration of maternal and child health (MCH) and immunization services as a strategy to strengthen immunization programs. We...

Valganciclovir: An advance in cytomegalovirus therapeutics

2002

OBJECTIVE: To review the pharmacology, pharmacokinetics, and preliminary clinical data for valganciclovir, a new oral agent for the therapy of cytomegalovirus (CMV) retinitis. DATA SOURCES: Relevant literature was extracted via...

Evaluation and management of dyslipidemia in patients with HIV infection

2002

OBJECTIVE: Persons with HIV infection develop metabolic abnormalities related to their antiretroviral therapy and HIV infection itself. The objective of this study was to summarize the emerging evidence for the...

The intersections of HIV and violence: Directions for future research and interventions

2000

The purpose of this paper is to review the available literature on the intersections between HIV and violence and present an agenda for future research to guide policy and programs....

Text message intervention designs to promote adherence to antiretroviral therapy (ART): A meta-analysis of randomized controlled trials

2014

BACKGROUND: The efficacy of antiretroviral therapy depends on patient adherence to a daily medication regimen, yet many patients fail to adhere at high enough rates to maintain health and reduce...

Rapid point-of-care HIV testing in youth: A systematic review

2013

PURPOSE: This review examines the literature surrounding acceptability of, and preference for, rapid point-of-care (POC) human immunodeficiency virus (HIV) testing in youth, documents notification rates when youth were offered rapid...

A systematic review of the epidemiology, immunopathogenesis, diagnosis, and treatment of pleural TB in HIV-infected patients

2012

Background. High HIV burden countries have experienced a high burden of pleural TB in HIV-infected patients. Objective. To review the epidemiology, immunopathogenesis, diagnosis, and treatment of pleural TB in HIV-infected...

Comparative effectiveness of efavirenz-based antiretroviral regimens in resource-limited settings

2012

Efavirenz (EFV) is a non-nucleoside widely used as first-line therapy for HIV-1 infection. Most of the research available on EFV comes from trials performed in industrialized countries and only a...

Meta-analysis of HIV risk-reduction interventions within drug abuse treatment programs

2001

A meta-analysis was conducted on studies using a treatment-comparison group design to evaluate HIV/AIDS risk-reduction interventions for clients enrolled in drug abuse treatment programs. Overall, the interventions studied were found...

Systematic review of combination antiretroviral therapy with didanosine plus hydroxyurea: A partial solution to Africa’s HIV/AIDS problem?

2001

Effective antiretroviral therapy remains beyond the reach of most human immunodeficiency virus (HIV)-infected persons living in the third world because of its tremendous cost. The cancer drug, hydroxyurea, inhibits HIV-1...

Condom effectiveness in reducing heterosexual HIV transmission

2002

BACKGROUND: The amount of protection that condoms provide for HIV and other sexually transmitted diseases is unknown. Cohort studies of sexually active HIV serodiscordant couples with follow-up of the seronegative...

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