Category Archives: Population(s)
Adjunctive corticosteroids for Pneumocystis Jiroveci Pneumonia in patients with HIV-infection
BACKGROUND: Pneumocystis jiroveci pneumonia (PCP) remains the most common opportunistic infection in patients infected with the human immunodeficiency virus (HIV). Among patients with HIV infection and PCP the mortality rate...
Setting and organization of care for persons living with HIV/AIDS
BACKGROUND: Treating the world’s 40.3 million persons currently infected with HIV/AIDS is an international responsibility that involves unprecedented organizational challenges. Key issues include whether care should be concentrated or decentralized,...
Improving the prevention, diagnosis and treatment of TB among people living with HIV: The role of operational research
Operational research is necessary to improve the access to and delivery of tuberculosis prevention, diagnosis and treatment interventions for people living with HIV. We conducted an extensive review of the...
Patient retention in antiretroviral therapy programs in sub-Saharan Africa: A systematic review
BACKGROUND: Long-term retention of patients in Africa’s rapidly expanding antiretroviral therapy (ART) programs for HIV/AIDS is essential for these programs’ success but has received relatively little attention. In this paper...
Kidney and liver organ transplantation in persons with human immunodeficiency virus: An evidence-based analysis
The objective of this analysis is to determine the effectiveness of solid organ transplantation in persons with end stage organ failure (ESOF) and human immunodeficiency virus (HIV+) Clinical Need: Condition...
Partner notification for STI and HIV: Patients’ views and experiences of notifying partners
Background: Partner notification (PN) involves contacting the sexual and needle-sharing partners of patients diagnosed with STI/ HIV. Effective PN can prevent onward STI/HIV transmission. However, little is known about the...
Predictors of late presentation for HIV diagnosis: A literature review and suggested way forward
Early commencement of antiretroviral treatment can be beneficial and economical in the long run. Despite global advances in access to care, a significant proportion of adults presenting at HIV/AIDS care...
The effects of global health initiatives on country health systems: A review of the evidence from HIV/AIDS control
This paper reviews country-level evidence about the impact of global health initiatives (GHIs), which have had profound effects on recipient country health systems in middle and low income countries. We...
Efficacy and tolerability of initial antiretroviral therapy: A systematic review
OBJECTIVES: Successful antiretroviral therapy (ART) is largely attributed to the type of third drug. Guidelines recommend regimens without systematic review of all factors that might affect treatment success, such as...
Externalities of prevention of mother-to-child transmission programs: A systematic review
There has been considerable debate about the effects of targeted global health assistance in low- and middle-income countries on health systems, specifically HIV/AIDS funding. Recently, a handful of studies have...
