Category Archives: Population(s)

Etravirine as a switching option for patients with HIV RNA suppression: A review of recent trials

2014

Unlike other nonnucleoside reverse transcriptase inhibitors, etravirine is only approved for use in treatment-experienced patients. In the DUET 1 and 2 trials, 1203 highly treatment-experienced patients were randomized to etravirine...

A systematic review of psychological functioning of children exposed to HIV: Using evidence to plan for tomorrow’s HIV needs

2014

Prevention of mother to child transmission of HIV can virtually eliminate paediatric HIV infection. Studies are needed to understand child development outcomes for children exposed to HIV in utero but...

How does the mining industry contribute to sexual and reproductive health in developing countries? A narrative synthesis of current evidence to inform practice

2013

AIMS AND OBJECTIVES: To explore client and provider experiences and related health outcomes of sexual and reproductive health interventions that have been led by or that have involved mining companies....

Infections and inflammatory diseases as risk factors for venous thrombosis. A systematic review

2012

Inflammation and venous thrombosis are intertwined. Only in the recent 15 years clinical epidemiological studies have focussed on inflammatory or infectious diseases as risk factors for venous thrombosis. Although a...

HIV testing in community settings in resource-rich countries: A systematic review of the evidence

2012

OBJECTIVES: Community HIV testing represents an opportunity for diagnosing HIV infection among individuals who may not have contact with health services, especially in hard-to-reach groups. The aim of this review...

Population pharmacokinetic meta-analysis with efavirenz

2002

A population-based pharmaco-kinetic (PK) model has been developed for efavirenz based on 16 phase I studies. The combined data set consisted of 334 healthy volunteers, 2,907 efavirenz dose administrations and...

Prevention of sexual risk behavior for HIV infection with women

2000

This paper defines the components of gender-specific interventions for HIV infections for women, i.e. negotiation skills with male partners for condom use, integration of strategies against HIV and other STD...

Effective approaches to reducing adolescent unprotected sex, pregnancy, and childbearing

2002

In the United States, there exist a multitude of different approaches to reducing adolescent sexual risk-taking, unintended pregnancy, childbearing, and sexually transmitted disease, including HIV. While many of these approaches...

Treatment outcomes from community-based drug resistant tuberculosis treatment programs: A systematic review and meta-analysis

2014

BACKGROUND: There is increasing evidence that community-based treatment of drug resistant tuberculosis (DRTB) is a feasible and cost-effective alternative to centralized, hospital-based care. Although several large programs have reported favourable...

Improved access to early infant diagnosis is a critical part of a child-centric prevention of mother-to-child transmission agenda

2013

BACKGROUND: Prevention-of-mother-to-child-transmission (PMTCT) programs have made it possible to achieve dramatic reductions in the rate of vertical HIV transmission. However, high attrition, particularly after delivery, has limited the impact of...

Condom use in China: Prevalence, policies, issues and barriers

2012

In this review, we describe condom use and its influencing factors in China, with a particular focus on the five populations that are at high risk for HIV/sexually transmissible infections...

Family-centred approaches to the prevention of mother to child transmission of HIV

2010

Prevention of mother to child transmission (PMTCT) programmes have traditionally been narrow in scope, targeting biomedical interventions during the perinatal period, rather than considering HIV as a family disease. This...

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