Category Archives: Population(s)
Complications due to HIV in patients undergoing total joint arthroplasty: A systematic review and meta-analysis
Background: HIV infection in patients undergoing Total joint arthroplasty (TJA) results in adverse postoperative outcomes. However, there are uncertain data regarding the extent of involvement of HIV in TJA and the...
Prevalence and associated factors of HIV among female sex workers in Eastern and Southern Africa: Systematic review and meta-analysis
BACKGROUND: Female sex workers (FSWs) are marginalized groups of the population who have limited access to healthcare and a higher risk of HIV infection due to biobehavioral and structural risk...
Is racism a barrier to HIV care continuum engagement among Black People in the United States? A scoping review to assess the state of the science and inform a research agenda
People living with HIV can achieve viral suppression through timely HIV care continuum (HCC) engagement (ie, diagnosis, linkage to HIV care, retention in care, and adherence to prescribed treatment regimens)....
Unintended pregnancy among women living with HIV and its predictors in East Africa, 2024. A systematic review and meta-analysis
INTRODUCTION: An unintended pregnancy refers to a situation where a pregnancy occurs either when there is no desire for a child (unwanted) or when it takes place at a time...
The prevalence of low-level viraemia and its association with virological failure in people living with HIV: A systematic review and meta-analysis
Low-level viraemia (LLV) following antiretroviral therapy (ART) in people living with HIV (PLWH) has not received sufficient attention. To the determine the prevalence of LLV and its association with virological...
Barriers to PrEP use and adherence among adolescent girls and young women in Eastern, Southern, and Western Africa: A scoping review
BACKGROUND: Adolescent girls and young women (AGYW) are disproportionately affected by HIV. Globally, in 2022, an estimated 4000 AGYW 15–24 were newly infected with HIV weekly, and nearly 78% of...
Prevalence, predictors, and outcomes of HIV care in HIV-positive clients entering HIV care with advanced HIV disease in sub-Saharan Africa 2010–2022: Systematic review and meta-analysis
Background and aims: Sub-Saharan Africa drives global HIV-related mortality, and patients continuously present with advanced HIV disease (AHD) at diagnosis. We describe prevalence, predictors, and treatment outcomes in HIV clients with...
Adverse birth outcome research case definitions associated with maternal HIV and antiretroviral drug use in pregnancy: A scoping review
Introduction: The global antiretroviral therapy era has led to a decline in the number of children newly acquiring HIV and an increase in the number of children who are HIV-exposed and...
Understanding human papillomavirus vaccine response and efficacy in people living with HIV: A systematic mixed studies review and meta-analysis
Coinfection with human papillomavirus (HPV) and HIV compounds the risks of developing cervical, anal, and HPV-associated oral neoplasia. Safe prophylactic vaccines are available to prevent HPV infections in people with...
Caring for a young child who is HIV exposed and whose HIV status is not yet known: A scoping review of mothers’ experiences
Living with HIV can affect mothers’ wellbeing, functioning, and experiences of caregiving. Most research about caregiving in the context of HIV comes from studies of dyads where both mother and...
Adherence to antiretroviral therapy and its associated factors among children living with HIV in Eastern and Southern Africa: A systematic review and meta-analysis
Background: Children living with HIV in low-income settings, such as in Eastern and Southern Africa, are at a high risk for poor adherence to antiretroviral therapy. However, various primary studies presented...
Genetic variation on dolutegravir pharmacokinetics and relation to safety and efficacy outcomes: A systematic review
BACKGROUND: Dolutegravir (DTG) is an antiviral agent used for the treatment of HIV, however, there is uncertainty over the influence of genetic variation on DTG exposure, and whether it has...
