Category Archives: Population(s)
Limited benefit of antiretroviral resistance testing in treatment-experienced patients: A meta-analysis
OBJECTIVE: To estimate the effectiveness of resistance assessments based on viral sequencing (genotypic antiretroviral resistance testing, GART), phenotypic antiretroviral resistance testing (PART) or virtual PART (vPART) in the management of...
Is the virulence of HIV changing? A meta-analysis of trends in prognostic markers of HIV disease progression and transmission
OBJECTIVE: The potential for changing HIV-1 virulence has significant implications for the AIDS epidemic, including changing HIV transmission rates, rapidity of disease progression, and timing of ART. Published data to...
Mother’s CD4+ count moderates the risk associated with higher parity for late postnatal HIV-free survival of breastfed children: An individual patient data meta-analysis of randomized controlled trials
Risk association studies of late postnatal outcomes for children breastfed by HIV-1 positive mothers have had inconsistent findings and have not explored interactions among risk factors. This study addresses these...
A review of studies assessing the costs and consequences of interventions to reduce mother-to-child HIV transmission in sub-Saharan Africa
OBJECTIVE: To review the methods and findings of studies that assess the costs and consequences of interventions to reduce mother-to-child HIV transmission in sub-Saharan Africa. DESIGN: Systematic literature review. METHODS:...
Treatment of cryptosporidiosis in immunocompromised individuals: Systematic review and meta-analysis
Cryptosporidium is a common cause of gastroenteritis and is associated with severe life-threatening illness among immunocompromised individuals. This review aimed to assess the efficacy of interventions for the treatment and...
Efficacy of group psychotherapy to reduce depressive symptoms among HIV-infected individuals: A systematic review and meta-analysis
Depressed mood is highly prevalent among HIV-infected individuals. Some but not all studies have found group psychotherapy to be efficacious in this population. We performed a systematic review and meta-analysis...
Post-HAART outcomes in pediatric populations: Comparison of resource-limited and developed countries
CONTEXT: No formal comparison has been made between the pediatric post-highly active antiretroviral therapy (HAART) outcomes of resource-limited and developed countries. OBJECTIVE: To systematically quantify and compare major baseline characteristics...
A systematic review of school-based sexual health interventions to prevent STI/HIV in sub-Saharan Africa
BACKGROUND: The HIV/AIDS epidemic remains of global significance and there is a need to target (a) the adolescent age-groups in which most new infections occur; and (b) sub-Saharan Africa where...
