Category Archives: Population(s)

Bidirectional relationship between HIV/HBV infection and comorbid depression and/or anxiety: A systematic review on shared biological mechanisms

2023

Background: Mental disorders that are comorbid with chronic infectious diseases may worsen clinical outcomes and patients’ quality of life. We hypothesized that depression and/or anxiety syndromes or symptoms comorbid with...

Influences affecting decision-making regarding use of pre-exposure prophylaxis among black men who have sex with men in the USA: A systematic review and meta-synthesis

2023

AIM: To systematically identify, evaluate, and synthesise qualitative research examining positive and negative influences affecting decision-making behaviour among black men who have sex with men (BMSM) in the USA regarding...

Overcoming structural barriers to diffusion of HIV pre-exposure prophylaxis

2023

HIV prevention with antiretroviral medication in the form of pre-exposure prophylaxis (PrEP) offers a critical tool to halt the HIV pandemic. Barriers to PrEP access across drug types, formulations, and...

Fixed-dose antiretroviral combinations in children living with human immunodeficiency virus type 1 (HIV-1): A systematic review

2023

Fixed-Dose antiretroviral Combinations (FDCs) are the most used drug regimes in adult patients with human-immunodeficiency virus 1 infection, since they increase adherence to antiretroviral therapy and enable good quality of...

Prevalence of obesity, hypertension and diabetes among people living with HIV in South Africa: A systematic review and meta-analysis

2023

Background HIV has become a manageable chronic condition due to the success and scale-up of antiretroviral therapy (ART). Globally, South Africa has the highest number of people living with HIV...

Non-adherence to anti-retroviral therapy among adult people living with HIV in Ethiopia: Systematic review and meta-analysis

2023

Human immunodeficiency virus remains a global public health problem. Despite efforts to determine the prevalence of non-adherence to ART and its predictors in Ethiopia, various primary studies presented inconsistent findings....

Enacted stigma influences bereavement coping among children orphaned by parental AIDS: A longitudinal study with network analysis

2023

PURPOSE: The study aims to understand how enacted stigma influences bereavement coping at the style (scale) level and the specific pathways at the strategy (item) level. METHODS: The longitudinal data...

Nutrition counselling and clinical outcomes in HIV: A systematic review and meta-analysis

2023

Background: People living with the HIV (PLHIV) are at an increased risk of various diseases due to a weakened immune system, particularly if they are naïve or poorly adherent to antiretroviral...

Stigmatizing and inaccessible: The perspectives of female sex workers on barriers to reproductive healthcare utilizationAA scoping review

2023

AIM: To systematically map the extent, range and nature of qualitative studies that explored female sex workers’ own perspectives on barriers to accessing reproductive healthcare services. DESIGN: A scoping review...

Adverse effects of daily oral pre-exposure prophylaxis in men who have sex with men and transgender women: A systematic review and meta-analysis

2023

The adverse effects of oral pre-exposure prophylaxis (PrEP) using tenofovir disoproxil fumarate are barriers to PrEP initiation and continuation. Although serious effects are rare and predictable, evidence for this assessment...

Geographic and population distributions of human immunodeficiency virus (HIV)-1 and HIV-2 circulating subtypes: A systematic literature review and meta-analysis (2010–2021)

2023

BACKGROUND: HIV poses significant challenges for vaccine development due to its high genetic mutation and recombination rates. Understanding the distribution of HIV subtypes (clades) across regions and populations is crucial....

Barriers and facilitators for interventions to improve ART adherence in Sub-Saharan African countries: A systematic review and meta-analysis

2023

BACKGROUND: The HIV/AIDS pandemic remains a significant public health issue, with sub-Saharan Africa (SSA) at its epicentre. Although antiretroviral therapy (ART) has been introduced to decrease new infections and deaths,...

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