Category Archives: Population(s)
Cabotegravir plus rilpivirine injection for virally suppressed persons with HIV-1 infection: A systematic review and meta-analysis of randomized controlled trials
Purpose: This study evaluated the efficacy and safety of cabotegravir/rilpivirine long-acting formulation compared to oral standard of care at 48 and 52 weeks. Method: We conducted an electronic search (2005-2024) across databases...
Cannabis use and HIV among Black sexually minoritized men: A systematic review and narrative analysis
Objective: We conducted a systematic review evaluating the extant literature examining the impacts of cannabis use on HIV-related outcomes among Black sexual minoritized men (BSMM). Design: A systematic review. Methods: We conducted a...
Pharmacokinetic adaptations in pregnancy: Implications for optimizing antiretroviral therapy in HIV-positive women
Pregnancy introduces significant physiological changes that alter the pharmacokinetics (PK) of antiretroviral therapy (ART), impacting its safety and efficacy in HIV-positive women. Optimizing ART during pregnancy is critical to maintaining...
Comparative safety of B/F/TAF versus other antiretroviral therapy regimens for treatment-naïve people with HIV-1: A systematic literature review and network meta-analysis
Aim: Bictegravir, emtricitabine and tenofovir alafenamide (B/F/TAF) is a single-tablet regimen approved for the treatment of HIV-1 in treatment-naive (TN) and virologically suppressed people with HIV-1 (PWH). While the efficacy of...
Prevalence of suicidal ideation, suicide attempts and suicide deaths in people living with HIV: Are there differences between geographic locations or sexes? : An overview of systematic reviews with meta-analysis
BACKGROUND: Preventing suicide is an important clinical and research priority according to the World Health Organization across lifespan. OBJECTIVE: This study summarizes the prevalence of suicidal ideation, attempts, and suicide...
The effectiveness of monetary incentives in improving viral suppression, treatment adherence, and retention in care among the general population of people living with HIV: A systematic review and meta-analysis
Background Achieving and maintaining viral suppression and optimal adherence to antiretroviral therapy are crucial for improving health outcomes in general population of people living with HIV. This study aimed to...
Impact of mHealth on enhancing pre-exposure prophylaxis adherence and strengthening the HIV prevention cascade among key populations: A systematic review and meta-analysis
Background Good adherence to pre-exposure prophylaxis (PrEP) is critical for effective HIV prevention. Despite the growing awareness of PrEP, many individuals remain at a preliminary understanding stage and struggle to...
Systematic review of infodemiology studies using artificial intelligence: Social media posts on HIV preexposure prophylaxis
OBJECTIVES: To explore how artificial intelligence (AI) can enhance infodemiology, which distributes and scans information in the electronic medium, to process social media posts for HIV preexposure prophylaxis (PrEP). DESIGN:...
Prevalence of HIV drug resistance among patients experiencing first-line treatment failure in Ethiopia: A systematic review and meta-analysis
Background The emergence of human immunodefiency virus (HIV) drug resistance presents a substantial challenge. Alternatives for effective treatment regimens are limited, and treatment strategies are complicated. Although a number of...
Are Candida albicans isolates from people living with HIV more resistant to antifungals? A systematic review and meta-analysis
People living with HIV (PLHIV) often require antifungal medications for the treatment or prevention of infections, which may contribute to the emergence of resistant Candida albicans strains. This systematic review...
Harms associated with injecting in public spaces: A global systematic review and meta-analysis
BACKGROUND: Despite increasing backlash against harm reduction efforts and the need to understand the risk environments encountered by people who inject drugs (PWID), a quantitative systematic review on public injecting...
