Category Archives: Population(s)

BACKGROUND: Breastfeeding is essential for ensuring the health and survival of children, particularly in regions where diarrhoea, pneumonia and malnutrition are common causes of child mortality. In sub-Saharan Africa, over...

Objectives: This study aimed to estimate the prevalence of M. genitalium infection and understand the patterns of resistance associated mutations (resistance hereafter) in people with HIV (PWH). Methods: We searched PubMed-MEDLINE, Embase...

Background: Cryptococcal disease is considered a major cause of morbidity in individuals with HIV in resource-limited settings. The long-term effects of COVID-19 and cryptococcal coinfection among people living with HIV (PLWHIV)...

Background Clinical trials have shown the protective efficacy of tuberculosis preventive treatment (TPT) for averting disease and death from tuberculosis among people living with HIV/AIDS (PLHIV). TPT has been recommended...

Background Human immunodeficiency virus (HIV) and COVID-19 continue to pose significant global public health challenges. Although vaccination is essential for preventing COVID-19 in people with HIV (PWH), evidence on the...

Background C-X-C motif chemokine ligand 10 (CXCL10) is implicated in HIV-associated neuroinflammation, yet its association with HIV-associated neurocognitive disorders (HAND) remains unclear. We conducted a meta-analysis to evaluate cerebrospinal fluid...

Background: Tuberculosis (TB) incidence and mortality in people living with HIV can be reduced by TB preventive treatment (TPT). However, low levels of screening and uptake, poor adherence, and loss to...

Background Eliminating HIV vertical transmission is a global priority and monitored by estimating paediatric HIV infections with the UNAIDS-supported Spectrum AIDS Impact Module (Spectrum-AIM). Recent innovations in antiretroviral therapy (ART)...

BACKGROUND: The long-acting injectable regimen of cabotegravir plus rilpivirine (CAB/RPV) emerged as an alternative to oral standard-of-care integrase strand transfer inhibitor (INSTI)-based regimens for individuals with adherence challenges or preference...

INTRODUCTION: This systematic review synthesizes recent evidence on the cost-effectiveness of HIV prevention interventions in sub-Saharan Africa (SSA), where over 70% of the global HIV burden resides. METHODS: Following PRISMA...

PURPOSE: We conducted a systematic review of studies comparing the intensity of epigenetic ageing in people living with human immunodeficiency virus (HIV) and uninfected individuals. We included studies that quantitatively...

Background People living with HIV (PLWH) have rising life expectancy, and robust evidence shows they are also at increased risk of cardiovascular disease. However, sudden cardiac death (SCD) for PLWH...