Category Archives: Population(s)

Morbidity and mortality in tuberculosis associated immune reconstitution inflammatory syndrome in children living with HIV: A narrative review

2023

Tuberculosis-associated immune reconstitution syndrome (TB-IRIS) is an increasingly recognized complication of children living with HIV who are receiving treatment for active tuberculosis (TB). The purpose of the study was to...

Attrition one year after starting antiretroviral therapy before and after the programmatic implementation of HIV “Treat All” in Sub-Saharan Africa: A systematic review and meta-analysis

2023

Introduction Evidence on the real-world effects of “Treat All” on attrition has not been systematically reviewed. We aimed to review existing literature to compare attrition 12 months after antiretroviral therapy (ART)...

Systematic review of prevalence and risk factors of transfusion transmissible infections among blood donors, and blood safety improvements in Southern Africa

2023

Blood and blood products are listed as one of the essential medicines by the World Health Organization (WHO). In addition to inadequate supply, most sub-Saharan Africa (SSA) nations fail to...

Provision of HIV prevention and care services to farmworkers in sub-Saharan African countries

2023

OBJECTIVES: To summarise data on human immunodeficiency virus (HIV) services available to farmworkers in sub-Saharan Africa (SSA). METHODS: We conducted a systematic review to understand which HIV prevention and care...

A systematic review of qualitative research on recently acquired HIV

2023

OBJECTIVES: Recently acquired HIV is a critical time when people may experience debilitating symptoms and is when they are most likely to pass HIV on. Qualitative research offers insights into...

The use of non-invasive imaging modalities for the assessment of skeletal muscle quantity and quality in people with HIV: A narrative review

2023

BACKGROUND: People with HIV (PWH) are prone to mobility impairments and physical dysfunction, with the loss of skeletal muscle quantity and quality being a major contributor to the dysfunction. Assessment...

Pharmacokinetics of antiretroviral drugs in older people living with HIV: A systematic review

2023

Background and objective: The life expectancy of people living with HIV (PLWHIV) has significantly improved in recent decades, mostly due to antiretroviral (ARV) therapy. Aging can affect the pharmacokinetics of drugs...

Global associations of key populations with HIV-1 recombinants: A systematic review, global survey, and individual participant data meta-analysis

2023

INTRODUCTION: Global HIV infections due to HIV-1 recombinants are increasing and impede prevention and treatment efforts. Key populations suffer most new HIV infections, but their role in the spread of...

Geographic and population distributions of HIV-1 and HIV-2 circulating subtypes: A systematic literature review and meta-analysis (2010–2021)

2023

BACKGROUND: HIV continues to be a major source of morbidity and mortality. Among the main challenges faced by prophylactic HIV vaccine development are the high rates of genetic mutation and...

MiRNA expression profiling in HIV pathogenesis, disease progression and response to treatment: A systematic review

2023

Aim: A systematic review was conducted to identify the association of miRNA expression with HIV pathogenesis, progression and treatment. Methods: A search of articles was conducted in MEDLINE®, Cochrane Central Register of Controlled...

Incidence and prevalence of hepatitis C virus among HIV-negative gay and bisexual men using HIV pre-exposure prophylaxis (PrEP): A systematic review and meta-analysis

2023

BACKGROUND: Gay and bisexual men using HIV pre-exposure prophylaxis (PrEP) are at increased risk for sexually transmissible infections. Hepatitis C virus (HCV) risk among PrEP users is less clear. We...

HIV stigma reduction interventions among health care providers and students in different countries: A systematic review

2023

BACKGROUND: Health care providers’ stigmatizing attitudes are obstacles to patients’ well-being and quality of life. Dealing with HIV-related stigma and understanding the impact of feasible interventions on reducing stigmatizing attitudes...

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