Category Archives: Population(s)

Microalbuminuria among HIV/AIDS patients in Africa: A systematic review and meta-analysis

2025

Background Over the past decade, the incidence of chronic kidney disease among HIV-seropositive people has increased at an alarming rate. Microalbuminuria is believed to be a precursor of HIV-related renal...

Evolving landscape of economic evaluations of HIV pre-exposure prophylaxis and pre-exposure prophylaxis implementation strategies: A systematic review

2025

INTRODUCTION: Economic evaluations of HIV pre-exposure prophylaxis (PrEP) and associated implementation strategies guide evidence-based policies, programmes and resource allocation. Since 2015, there has been an evolution in PrEP modalities, implementation...

Long-acting injectable cabotegravir and rilpivirine in observational cohort studies: A systematic review on virological failure, resistance and re-suppression outcomes in virally suppressed individuals living with HIV

2025

Introduction Randomized controlled trial evidence suggests that long‐acting injectable (LA‐I) cabotegravir and rilpivirine (CAB+RPV) has similar virological failure (VF) rates to daily oral therapy, but clinical practice evidence is lacking....

Reducing HIV risk behaviors among Black women living with and without HIV/AIDS in the U.S.: A systematic review

2025

This systematic review provides an examination of the status of HIV/AIDS prevention interventions for Black, heterosexual women in the U.S. from 2012 to 2019. Using PRISMA guidelines, 28 interventions were...

Barriers to and facilitators of heterosexual men’s engagement with the PrEP care continuum in Sub-Saharan Africa: A scoping review

2025

The HIV epidemic in sub-Saharan Africa (SSA) continues to spread primarily through heterosexual contact, and in many countries, heterosexual men continue to exhibit a high HIV incidence with resultant morbidity...

Dolutegravir + lamivudine effectiveness and tolerability in real-world cohorts with HIV-1 across Asia and South America: A systematic literature review

2025

Background: Dolutegravir (DTG) + lamivudine (3TC) has demonstrated efficacy and safety in phase 3 clinical trials; however, most published data are from people with HIV-1 in North America and Europe. Methods: To...

Gut microbiota of sub-Saharan Africa infants exposed to antiretroviral therapy: Scoping review

2025

Background Antiretroviral (ARV) exposure influences the early-life gut microbiota in regions with high human immunodeficiency virus (HIV) burdens. Understanding how ARV drugs affect the infant gut microbiota is important for...

Evaluating the impact of COVID-19 on the HIV care continuum across global income levels: A mixed-methods systematic review

2025

BACKGROUND: The COVID-19 pandemic caused significant disruptions to global healthcare systems, including essential services along the HIV care continuum (HCC). While several studies have examined these impacts in specific countries...

Psychosocial experience and coping of AIDS patients about the disease: A systematic review and qualitative meta-synthesis

2025

AIM: To systematically integrate the psychosocial experiences and coping mechanisms of AIDS patients after the disease, and to understand their true feelings, in order to provide a basis for better...

Studied factors and metrics of patient portal use among people with HIV: A rapid scoping review

2025

For people living with HIV (PLHIV), patient portals could facilitate access to personal health records while promoting self-management and retention in care. Given the apparent heterogeneity in the studied factors...

Prevalence and epidemiological distribution of substance use among people living with HIV in the East African region: A meta-analysis

2025

BACKGROUND: The East African region lacks synthesised scientific evidence on the impact of different substances used on HIV management and treatment outcomes in this population. We meta-analysed epidemiological data on...

Incidence and predictors of attrition among children on antiretroviral therapy in Ethiopia: A systematic review and meta-analysis

2025

Objective To estimate the pooled attrition rate among HIV-infected children receiving antiretroviral therapy (ART) and identify predictors of attrition in Ethiopia. Design Systematic review and meta-analysis. Data sources PubMed, HINARI,...

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