Category Archives: Population(s)

Systematic scoping review on HIV services for males in Sub-Saharan Africa: Access, barriers, and research gaps

2026

BACKGROUND: Access to HIV services among men and boys in Sub-Saharan Africa is a significant public health challenge, exacerbated by cultural norms surrounding masculinity. This scoping review systematically investigates disparities...

Machine Learning in HIV Care and Antiretroviral Therapy: Systematic Review

2026

BACKGROUND: Artificial intelligence (AI) is expanding across various medical fields, with machine learning (ML) being increasingly used to enhance patient management in diagnosis, prevention, and therapeutic care. OBJECTIVE: This study...

Circumcision for HIV Prevention in Men Who Have Sex With Men: An Updated Meta-Analysis

2026

BACKGROUND: Circumcision reduces HIV risk for men who have sex with women, but for men who have sex with men (MSM), prior meta-analyses were ambiguous because of inconsistent, highly confounded...

Gender-responsive and -transformative interventions in HIV, TB and malaria programmes: A review of evidence

2026

Gender-responsive and -transformative interventions are essential for tackling harmful social norms and discriminatory laws, policies, and practices that drive gender inequalities and health inequities especially for women, girls, and gender-diverse...

Risk factors for HIV-associated neurocognitive impairment and frailty in aging people with HIV in Latin America: A systematic review

2026

No abstract available

Effects of Digital Health Interventions to Promote Safer Sex Behaviors Among Youth: Systematic Review and Bayesian Network Meta-Analysis

2026

BACKGROUND: Youth aged 15-24 years carry a disproportionate HIV/sexually transmitted infections (STIs) burden. In recent years, different modalities of digital health interventions (DHIs) have been explored to promote safer sex...

Perceptions About the Relationship Between HIV, Antiretroviral Therapy (ART), and Fecundity in Sub-Saharan Africa: Findings from a Systematic Scoping Review

2026

Advances in antiretroviral therapy (ART) enable women living with HIV to safely conceive and give birth without vertical transmission. However, in sub-Saharan Africa, 1 in 6 people experience infertility and...

Age-specific distribution of cervical precancer and cancer among women living with HIV across seven countries: A systematic review and an individual patient data meta-analysis

2026

BACKGROUND: Women living with HIV have an elevated risk for cervical cancer, present earlier, and have more recurrent human papillomavirus (HPV) infections compared with women without HIV. To update WHO...

Polypharmacy in HIV: Rethinking what counts and why it matters

2025

Polypharmacy, the concurrent use of multiple medications, presents a growing challenge in HIV care as people living with HIV age and experience earlier onset of age-related co-morbidities. However, how polypharmacy...

Doxycycline prophylaxis is effective as pre-exposure and post-exposure regimens in the prevention of sexually transmitted infections: An updated systematic review and meta-analysis

2026

BACKGROUND: Recent systematic reviews have demonstrated the efficacy of doxycycline prophylaxis in preventing bacterial sexually transmitted infections (STIs)Aÿin randomised controlled trials (RCTs). In this review, we updated evidence from RCTs...

HIV and cardiovascular diseases: A systematic review and comparative risk assessment study

2026

BACKGROUND: People living with HIV (PLWH) face a significantly elevated risk of cardiovascular diseases (CVDs). This study aims to quantify temporal trends in HIV-attributable CVD burden at global, regional and...

Interventions for thriving in HIV serodiscordant relationships in Sub-Saharan Africa: a scoping review

2026

BACKGROUND: HIV serodiscordant relationships, where one partner is HIV-positive and the other is HIV-negative, present unique challenges despite biomedical advances including Uƒ_%=ƒ_%U (Undetectableƒ_%=ƒ_%Untransmittable). Effective interventions are crucial to support these...

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