Category Archives: Population(s)
Organization and integration of care in the HIV-non-communicable disease syndemic: A rapid scoping review
Advances in antiretroviral therapy have transformed infection with HIV into a manageable chronic disease, increasing the survival of people living with HIV, who are also undergoing a demographic aging process...
Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications
Dolutegravir underpins modern first- and second-line HIV treatment regimens; however, interindividual variability in its disposition and tolerability presents challenges for optimal use. This scoping review mapped current evidence on the...
Prevalence and risk of cardiovascular events among people living with HIV: A meta-analysis
BACKGROUND: People living with HIV (PLWH) have increased cardiovascular risk, but the contribution of HIV-related factors to all-cause cardiovascular events remains unclear. We assessed the prevalence and determinants of cardiovascular...
Prevalence of HIV and hepatitis B co-infection in Nigeria: A systematic review and meta-analysis
Introduction Hepatitis B virus (HBV) and Human Immunodeficiency virus (HIV) infections are both major public health concerns in sub-Saharan Africa. Co-infection with these virus accelerates liver disease progression, increases hepatotoxicity,...
A systematic review of obstetric mistreatment among women living with HIV
Several studies have established that women living with HIV frequently encounter mistreatment when accessing maternal healthcare. Previous reviews on obstetric mistreatment have largely focused on the general population, leaving an...
Retention in care among women with HIV: A systematic review of treatment continuity during pregnancy and postpartum
Introduction Pregnant women with HIV are at risk of reduced engagement in HIV care during pregnancy and postpartum. Retention in care, defined as continuous engagement in HIV-related treatment and follow-up,...
Characterisation of HIV-1 gag cytotoxic T-lymphocyte epitopes in the southern African region—A systematic review
During early HIV‐1 infection, robust Cytotoxic T‐lymphocyte (CTL) responses are mostly targeted at immunodominant Gag p24 epitopes to reduce HIV‐1 viraemia to a set‐point. The aim of this study was...
Prevalence of cardiometabolic diseases among ART-naïve people with HIV: A global systematic review and meta-analysis
Introduction The burden of cardiometabolic diseases (CMDs) is rising in people with HIV (PWH). While extensive data exist on CMD prevalence in PWH receiving antiretroviral therapy (ART), comprehensive data on...
Burden and clinical impact of ‘neglected’ transfusion-transmitted infections in Cameroon: A systematic review and meta-analysis
Background Blood supply is a public health challenge in African countries. In Cameroon, blood selection guidelines focus on four viral and bacterial pathogens (HIV, hepatitis B and C viruses, Treponema pallidum)...
Barriers and facilitators to healthcare access among Sub-Saharan African migrants in Europe: A scoping review
Background Sub-Saharan African (SSA) migrants represent a significant and growing proportion of Europe’s diverse migrant population; yet face substantial barriers in accessing healthcare services. Understanding these barriers is essential for...
Burden of malaria-HIV coinfection and associated adverse outcomes in Ethiopia: A systematic review and meta-analysis
Background The co-occurrence of malaria and HIV represents a significant health crisis in sub-Saharan Africa, particularly in Ethiopia, where both diseases are prevalent. This synergistic burden aggravates health inequalities, strains...
