Category Archives: Children or Youth (less than 18 years old)

Challenges of the postpartum period in women living with HIV

2024

Key take-home messages

Proportion of active tuberculosis among HIV-infected children after antiretroviral therapy in Ethiopia: A systematic review and meta-analysis

2024

Despite effectiveness of antiretroviral therapy in reducing mortality of opportunistic infections among HIV infected children, however tuberculosis (TB) remains a significant cause for morbidity and attributed for one in every...

Incidence density mortality rate among HIV-positive children on antiretroviral therapy in Ethiopia: A systematic review and meta-analysis

2024

BACKGROUND: Human Immunodeficiency Virus (HIV) continues to be the major cause of childhood deaths, particularly in the sub-Saharan African region. In Ethiopia, though several primary studies have been conducted on...

Digital technology for HIV self-management in low- and middle-income countries: A scoping review of adolescents’ preferences

2024

Digital health technology interventions have shown promise in enhancing self-management practices among adolescents living with Human Immunodeficiency Virus (ALHIV). The objective of this scoping review was to identify the preferences...

Caregiver-assisted testing with HIV self-test kits for children 18 months and older: A GRADE systematic review

2024

Caregiver-assisted testing using HIV self-test (CG-HIVST) kits has been proposed to enhance paediatric HIV case finding and contribute toward ending paediatric HIV/AIDS by 2030. We conducted a systematic review to...

Evidence gaps in economic evaluations of HIV interventions targeting young people: A systematic review

2024

Purpose: Young people living with HIV (YPLWH) face the burden of navigating the unique physical, psychological, and social challenges of adolescence while coping with a stigmatized infectious disease that requires lifelong...

A conceptualization and psychometric evaluation of positive psychological outcome measures used in adolescents and young adults living with HIV: A mixed scoping and systematic review

2024

INTRODUCTION: Sub-Saharan Africa bears the greatest burden of HIV, with comorbid mental conditions highly prevalent in people living with HIV. It is important to evaluate the mental health of adolescents...

Perineal disintegration syndrome (PDS) in children with human immunodeficiency virus (HIV) infection: A scoping review

2024

BACKGROUND: Paediatric healthcare for children with HIV involves managing complex challenges, including severe perineal issues that significantly affect their quality of life. We introduce the term “perineal disintegration syndrome” (PDS)...

Prevalence of mental disorders among young people living with HIV: A systematic review and meta-analysis

2024

OBJECTIVE: This meta-analysis aims to evaluate the global prevalence of mental disorders among young people living with HIV. METHODS: A comprehensive search was conducted of the PubMed, Embase, and Cochrane...

Innovative pre-exposure prophylaxis interventions among adolescent girls and young women during COVID-19 lockdown period in sub-Saharan Africa: A systematic review

2024

Adolescent girls and young women are key, and priority populations impacted by a higher risk of acquiring human immunodeficiency virus. In 2015, pre-exposure prophylaxis was introduced as a biomedical human...

Treatment failure among Sub-Sahara African children living with HIV: A systematic review and meta-analysis

2024

BACKGROUND: Antiretroviral treatment failure is a global issue, particularly in developing countries such as Sub-Saharan Africa. Prior research findings were highly variable and inconsistent across areas. As a result, the...

Global, regional, and national prevalence of HIV-1 drug resistance in treatment-naive and treatment-experienced children and adolescents: A systematic review and meta-analysis

2024

Background Despite significant reductions in mother-to-child HIV-1 transmission risks due to the advancements and scale-up of antiretroviral therapy (ART), the global burden of HIV-1 drug resistance (HIVDR) in treatment-naive and...

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