Category Archives: Children or Youth (less than 18 years old)
A meta-analysis assessing diarrhea and pneumonia in HIV-exposed uninfected compared with HIV-unexposed uninfected infants and children
OBJECTIVE: Previous studies have demonstrated that HIV-exposed uninfected (HEU) infants and children experience morbidity and mortality at rates exceeding those of their HIV-unexposed uninfected (HUU) counterparts. We sought to summarize...
Which HIV-infected youth are at risk of developing depression and what treatments help? A systematic review focusing on Southern Africa
Background Depression is common in people with HIV and is associated with lower quality of life, reduced medication adherence, worse disease progression and higher risk of transmission to others. While...
Effectiveness of pneumococcal conjugate vaccination against invasive pneumococcal disease among children with and those without HIV infection: A systematic review and meta-analysis
BACKGROUND: HIV-infected children are at a higher risk of Invasive Pneumococcal Disease (IPD) and its mortality, even in the era of antiretroviral therapy. Therefore, an effective vaccination strategy would be...
HIV, syphilis, and viral hepatitis among Latin American indigenous peoples and Afro-descendants: A systematic review
Objective: To identify and summarize existing literature on the burden of HIV, sexually transmitted infections (STIs), and viral hepatitis (VH) in indigenous peoples and Afro-descendants in Latin America to provide...
A realist review of infant feeding counselling to increase exclusive breastfeeding by HIV-positive women in sub Saharan-Africa: What works for whom and in what contexts
BACKGROUND: The most recent World Health Organization (WHO) guidelines on Human Immunodeficiency Virus (HIV) and infant feeding promotes exclusive breastfeeding (EBF) in resource limited settings for the prevention of mother...
Causal effects of education on sexual and reproductive health in low and middle-income countries: A systematic review and meta-analysis
Background: Despite strong theoretical grounding, important gaps in knowledge remain regarding the degree to which there is a causal relationship between education and sexual and reproductive health, as many claims have...
Immunogenicity and safety of measles vaccine in HIV-infected children: An updated systematic review
Human immunodeficiency virus (HIV)-infected children are at increased risk of measles morbidity and mortality. We searched abstracts from the PubMed, Embase, and Latin American and Caribbean Health Sciences databases for...
Safety and immunogenicity of measles vaccination in HIV-infected and HIV-exposed uninfected children: A systematic review and meta-analysis
Background: HIV-infected and HIV-exposed uninfected (HEU) children have an increased risk of measles that may be due to altered immune responses or suboptimal timing of measles vaccination. We aimed to...
Risk factors for indeterminate interferon-gamma release assay for the diagnosis of tuberculosis in children-A systematic review and meta-analysis
Background: Interferon-gamma release assays (IGRA) are well-established immunodiagnostic tests for tuberculosis (TB) in adults. In children these tests are associated with higher rates of false-negative and indeterminate results. Age is...
Recent interventions to improve retention in HIV care and adherence to antiretroviral treatment among adolescents and youth: A systematic review
Adolescents represent a growing proportion of people living with HIV worldwide and the highest risk population group for treatment attrition and AIDS-related mortality. There is an urgent need to design,...
Pulmonary hypertension in the global population of adolescents and adults living with HIV: A systematic review and meta-analysis
A systematic review and meta-analysis was conducted to estimate the prevalence of PH in adolescents and adults living with HIV at the global level. PubMed, EMBASE, Web of Science, and...
