Category Archives: Children or Youth (less than 18 years old)

A systematic review on the influence of HLA-B polymorphisms on HIV-1 mother-to-child transmission

2019

BACKGROUND: Mother-to-child-transmission (MTCT) is the main route of HIV-1 infection in children. Genetic studies suggest HLA-B alleles play an important role on HIV-1 transmission, progression, and control of HIV-1 infection....

Pharmacokinetics and safety of the integrase inhibitors elvitegravir and dolutegravir in pregnant women with HIV

2019

OBJECTIVE: To synthesize data on the pharmacokinetics and safety of dolutegravir and elvitegravir in pregnant women living with HIV. DATA SOURCES: A PubMed, EMBASE, Web of Science, and Google Scholar...

Substance use and HIV among justice-involved youth: Intersecting risks

2019

PURPOSE OF REVIEW: This review discusses recent advances in research on the intersection of HIV prevention and substance use among youth involved with the justice system. We discuss current themes...

Stigma as experienced by children of HIV-positive parents: A narrative review

2019

This narrative review examines the effects on children of stigma by association with an HIV-positive parent. It expands on previous reviews by including all HIV-affected children, whether orphaned or living...

Anthroponotic transmission of cryptosporidium parvum predominates in countries with poorer sanitation: A systematic review and meta-analysis

2019

BACKGROUND: Globally cryptosporidiosis is one of the commonest causes of mortality in children under 24 months old and may be associated with important longterm health effects. Whilst most strains of...

Systematic mapping of relationship-level protective factors and sexual health outcomes among sexual minority youth: The role of peers, parents, partners, and providers

2018

Sexual minority youth (SMY) experience elevated rates of adverse sexual health outcomes. Although risk factors driving these outcomes are well studied, less attention has been paid to protective factors that...

Socio-structural factors influencing the prevention of mother-to-child transmission of HIV in the democratic republic of the Congo: A systematic review

2019

Introduction The Democratic Republic of the Congo (DRC) had the second-highest mother-to-child HIV transmission rate in Sub-Saharan Africa at 29% in 2013, however the uptake of preventive services for mother-to-child...

Postpartum women living with HIV: Challenges related to retention in care, treatment adherence, and mental health

2018

Key take-home messages Postpartum women living with HIV may find it challenging to remain engaged in HIV care and achieve optimal adherence to antiretroviral medications. Late entry or suboptimal engagement...

Experiences of the HIV cascade of care among indigenous peoples: A systematic review

2019

Indigenous leaders remain concerned that systemic oppression and culturally unsafe care impede Indigenous peoples living with HIV from accessing health services that make up the HIV cascade of care. We...

Paediatric postdischarge mortality in developing countries: A systematic review

2018

OBJECTIVES: To update the current evidence base on paediatric postdischarge mortality (PDM) in developing countries. Secondary objectives included an evaluation of risk factors, timing and location of PDM. DESIGN: Systematic...

Screening for HIV and linkage to care in adolescents: Insights from a systematic review of recent interventions in high- versus low- and middle-income settings

2018

Introduction: Compared to adults, adolescents and young adults have a higher incidence of HIV infection, yet lower rates of HIV testing. Few evidence-based interventions effectively diagnose new HIV infections among...

Transmission of drug-resistant tuberculosis in HIV-endemic settings

2018

The emergence and expansion of the multidrug-resistant tuberculosis epidemic is a threat to the global control of tuberculosis. Multidrug-resistant tuberculosis is the result of the selection of resistance-conferring mutations during...

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