Category Archives: Children or Youth (less than 18 years old)

Safety and immunogenicity of measles vaccination in HIV-infected and HIV-exposed uninfected children: A systematic review and meta-analysis

2019

Background: HIV-infected and HIV-exposed uninfected (HEU) children have an increased risk of measles that may be due to altered immune responses or suboptimal timing of measles vaccination. We aimed to...

Risk factors for indeterminate interferon-gamma release assay for the diagnosis of tuberculosis in children-A systematic review and meta-analysis

2019

Background: Interferon-gamma release assays (IGRA) are well-established immunodiagnostic tests for tuberculosis (TB) in adults. In children these tests are associated with higher rates of false-negative and indeterminate results. Age is...

Recent interventions to improve retention in HIV care and adherence to antiretroviral treatment among adolescents and youth: A systematic review

2019

Adolescents represent a growing proportion of people living with HIV worldwide and the highest risk population group for treatment attrition and AIDS-related mortality. There is an urgent need to design,...

Pulmonary hypertension in the global population of adolescents and adults living with HIV: A systematic review and meta-analysis

2019

A systematic review and meta-analysis was conducted to estimate the prevalence of PH in adolescents and adults living with HIV at the global level. PubMed, EMBASE, Web of Science, and...

A systematic global review of condom availability programs in high schools

2019

PURPOSE: High levels of HIV, sexually transmitted infections (STIs), and pregnancy among adolescents has motivated some countries to consider the implementation of condom availability programs (CAPs) in high schools. In...

Challenges and support for quality of life of youths living with HIV/AIDS in schools and larger community in East Africa: A systematic review

2019

BACKGROUND: Youths living with HIV/AIDS (YLWHA) experience innumerable challenges within schools and the larger community. Nonetheless, these environments are potential sources of support for such youths. This review provides a...

A systematic review on the influence of HLA-B polymorphisms on HIV-1 mother-to-child transmission

2019

BACKGROUND: Mother-to-child-transmission (MTCT) is the main route of HIV-1 infection in children. Genetic studies suggest HLA-B alleles play an important role on HIV-1 transmission, progression, and control of HIV-1 infection....

Pharmacokinetics and safety of the integrase inhibitors elvitegravir and dolutegravir in pregnant women with HIV

2019

OBJECTIVE: To synthesize data on the pharmacokinetics and safety of dolutegravir and elvitegravir in pregnant women living with HIV. DATA SOURCES: A PubMed, EMBASE, Web of Science, and Google Scholar...

Substance use and HIV among justice-involved youth: Intersecting risks

2019

PURPOSE OF REVIEW: This review discusses recent advances in research on the intersection of HIV prevention and substance use among youth involved with the justice system. We discuss current themes...

Stigma as experienced by children of HIV-positive parents: A narrative review

2019

This narrative review examines the effects on children of stigma by association with an HIV-positive parent. It expands on previous reviews by including all HIV-affected children, whether orphaned or living...

Health issues associated with commercial sexual exploitation and sex trafficking of children in the United States: A systematic review

2018

This article reviews studies examining health issues associated with commercial sexual exploitation and sex trafficking (CSE/ST) of children in the United States. We searched five health and social sciences databases...

Mental health and substance use in HIV-infected adolescents

2018

PURPOSE OF REVIEW: Adolescents with HIV include both those infected perinatally and behaviourally. This population is confronted by normative challenges and HIV stressors as they move towards becoming increasingly independent...

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