Category Archives: Children or Youth (less than 18 years old)

Adverse effects of oral second-line antituberculosis drugs in children

2016

INTRODUCTION: Increasing numbers of children with drug-resistant tuberculosis are accessing second-line antituberculosis drugs; these are more toxic than first-line drugs. Little is known about the safety of new antituberculosis drugs...

Cerebrovascular disease in children with HIV-1 infection

2016

An estimated 3.2 million children worldwide have human immunodeficiency virus (HIV) infection. Antiretroviral therapy (ART) has resulted in prolonged survival, leading to an increase in complications previously recognized in adults....

A critical review of the effectiveness of educational interventions applied in HIV/AIDS prevention

2015

OBJECTIVE: A critical review of issues around the effectiveness of educational approaches applied in the field of HIV/AIDS prevention. METHODS: Published papers, systematic reviews and technical reports were reviewed. RESULTS:...

Brief interventions to prevent sexually transmitted infections suitable for in-service use: A systematic review

2016

BACKGROUND: Sexually transmitted infections (STIs) are more common in young people and men who have sex with men (MSM) and effective in-service interventions are needed. METHODS: A systematic review of...

Performance of virological testing for early infant diagnosis: A systematic review

2017

BACKGROUND: Improved access to both maternal antiretroviral therapy (ART) and infant prophylaxis may have an impact on the performance of virological assays for diagnosis of HIV infection in infants. This...

The impact of HIV and antiretroviral therapy on TB risk in children: A systematic review and meta-analysis

2017

BACKGROUND: Children (

Barriers and enablers of the prevention of mother-to-child transmission of HIV/AIDS program in China: A systematic review and policy implications

2017

OBJECTIVE: To identify the barriers to and enablers of the prevention of mother-to-child transmission (PMTCT) of HIV program in China. METHODS: A systematic review of the existing literature regarding barriers...

Alarming increase in pretreatment HIV drug resistance in children living in sub-Saharan Africa: A systematic review and meta-analysis

2017

BACKGROUND: Children have an augmented risk of pretreatment HIV drug resistance (PDR) due to exposure to antiretroviral drugs for the prevention of mother-to-child transmission (PMTCT). Paediatric data are essential to...

Factors associated with HIV testing in youth in the United States: An integrative review

2016

We used an integrative review to synthesize existing literature on the factors associated with HIV testing by youth ages 13 to 24 years in the United States. PubMed, CINAHL, PsycINFO,...

Mortality in children diagnosed with tuberculosis: A systematic review and meta-analysis

2017

BACKGROUND: Case fatality ratios in children with tuberculosis are poorly understood-particularly those among children with HIV and children not receiving tuberculosis treatment. We did a systematic review of published work...

HIV-associated cognitive impairment in perinatally infected children: A meta-analysis

2016

CONTEXT: Research shows, conclusively, that perinatal HIV infection has negative effects on cognitive functioning of children and adolescents. However, the extent of these cognitive impairments is unknown. Current literature does...

Increased risk of group B streptococcus invasive infection in HIV-exposed but uninfected infants: A review of the evidence and possible mechanisms

2016

Group B Streptococcus (GBS) is a major cause of neonatal sepsis and mortality worldwide. Studies from both developed and developing countries have shown that HIV-exposed but uninfected (HEU) infants are...

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