Category Archives: Children or Youth (less than 18 years old)

Resourcing resilience: social protection for HIV prevention amongst children and adolescents in Eastern and Southern Africa

2016

Adolescents are the only age group with growing AIDS-related morbidity and mortality in Eastern and Southern Africa, making HIV prevention research among this population an urgent priority. Structural deprivations are...

Bone health and HIV in resource-limited settings: A scoping review

2016

PURPOSE OF REVIEW: Sub-Saharan Africa and other resource-limited settings (RLS) bear the greatest burden of the HIV epidemic globally. Advantageously, the expanding access to antiretroviral therapy (ART) has resulted in...

The impact of HIV and antiretroviral therapy on TB risk in children: A systematic review and meta-analysis

2017

BACKGROUND: Children (

Antiretroviral therapy adherence enhancing interventions for adolescents and young adults 13–24 years of age: A review of the evidence base

2016

INTRODUCTION: Youth living with HIV are highly under-represented in the evidence base for adherence interventions, despite their diverse and unique needs and barriers. OBJECTIVE: This systematic review aimed to identify...

School-based sexual health education interventions to prevent STI/HIV in sub-Saharan Africa: A systematic review and meta-analysis

2016

BACKGROUND: School-based sexual health education has the potential to provide an inclusive and comprehensive approach to promoting sexual health among young people. We reviewed evaluations of school-based sexual health education...

A systematic review of measures of HIV/AIDS stigma in paediatric HIV-infected and HIV-affected populations

2016

INTRODUCTION: HIV-related stigma impacts the quality of life and care management of HIV-infected and HIV-affected individuals, but how we measure stigma and its impact on children and adolescents has less...

Review of cytomegalovirus coinfection in HIV-infected individuals in Africa

2017

BACKGROUND: Cytomegalovirus (CMV) infection among HIV-infected individuals may cause end-organ disease, which is an AIDS-defining condition. Evidence from high-income countries suggests that CMV may alter the outcome of HIV infection,...

A comprehensive review of reviews of school-based interventions to improve sexual-health

2016

OBJECTIVE: To systematically review systematic reviews of school-based sexual-health and relationship Education (SHRE) programmes and, thereby, identify interventions and intervention components that promote reductions in risky sexual behaviour among young...

Suboptimal viral suppression rates among HIV-infected children in low- and middle-income countries: A meta-analysis

2016

BACKGROUND: The 90-90-90 goals aim to achieve viral suppression in 90% of all HIV-infected people on antiretroviral treatment (ART), which is especially challenging in children. Global estimates of viral suppression...

Why tell children: A synthesis of the global literature on reasons for disclosing or not disclosing an HIV diagnosis to children 12 and under

2016

While the psychological and health benefits of knowing one’s HIV diagnosis have been documented for adults and adolescents, practice is still in development for younger children. Moderating conditions for whether...

Paediatric HIV testing beyond the context of prevention of mother-to-child transmission: A systematic review and meta-analysis

2016

BACKGROUND: Many HIV-positive children in low-income and middle-income countries remain undiagnosed. Although HIV testing in children at health facilities is recommended by WHO, it is not well implemented. This systematic...

Perspectives and practice of HIV disclosure to children and adolescents by health-care providers and caregivers in sub-Saharan Africa: A systematic review

2016

BACKGROUND: Sub-Saharan Africa (SSA) has the highest prevalence of HIV globally, and this is due to persistent new HIV infections and decline in HIV/AIDS-related mortality from improved access to antiretroviral...

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