Category Archives: Children or Youth (less than 18 years old)
Interventions to prevent sexually transmitted infections, including HIV, among young people in low- and middle-income countries: A systematic review of the published and gray literature
Sexually transmitted infections (STIs), including HIV, are prevalent among adolescents and can have lasting adverse health consequences. The objective of this review is to identify high-quality interventions and evaluations to...
Scoping review: Strategies of providing care for children with chronic health conditions in low- and middle-income countries
OBJECTIVES: To identify and review strategies of providing care for children living with chronic health conditions in low- and middle-income countries. METHODS: We searched MEDLINE and Cochrane EPOC databases for...
Mobile phone interventions for adolescent sexual and reproductive health: A systematic review
CONTEXT: Interventions for adolescent sexual and reproductive health (ASRH) are increasingly using mobile phones but may not effectively report evidence. OBJECTIVE: To assess strategies, findings, and quality of evidence on...
Antiretroviral therapy adherence enhancing interventions for adolescents and young adults 13–24 years of age: A review of the evidence base
INTRODUCTION: Youth living with HIV are highly under-represented in the evidence base for adherence interventions, despite their diverse and unique needs and barriers. OBJECTIVE: This systematic review aimed to identify...
School-based sexual health education interventions to prevent STI/HIV in sub-Saharan Africa: A systematic review and meta-analysis
BACKGROUND: School-based sexual health education has the potential to provide an inclusive and comprehensive approach to promoting sexual health among young people. We reviewed evaluations of school-based sexual health education...
A meta-analysis assessing all-cause mortality in HIV-exposed uninfected compared to HIV-unexposed uninfected infants and children
OBJECTIVE: Conduct a meta-analysis examining differential all-cause mortality rates between HIV-exposed uninfected infants and children as compared to their HIV-unexposed uninfected counterparts. DESIGN: Meta-analysis summarizing the difference in mortality between...
Impact of HIV-status disclosure on adherence to antiretroviral therapy among HIV-infected children in resource-limited settings: A systematic review
Pediatric HIV remains a significant global health dilemma, especially in resource-constrained nations. As access to ART increases around the world, areas of concern in pediatric HIV treatment include age-appropriate disclosure...
Impact of maternal HIV-1 infection on the feto-maternal crosstalk and consequences for pregnancy outcome and infant health
Adaptation of the maternal immune system to establish maternal/fetal equilibrium is required for a successful pregnancy. Viral infections, including HIV-1 infection, can alter this maternal/fetal equilibrium, with significant consequences for...
What do we know about children living with HIV-infected or AIDS-ill adults in Sub-Saharan Africa? A systematic review of the literature
Millions of children in Sub-Saharan Africa live with adults, often parents, who are HIV-infected or ill due to AIDS. These children experience social, emotional, and health vulnerabilities that overlap with,...
Mycobacterium tuberculosis bacteremia in adults and children: A systematic review and meta-analysis
SETTINGp: Among human immunodeficiency virus (HIV) infected adults living in tuberculosis (TB) endemic settings, Mycobacterium tuberculosis is a common cause of bloodstream infections. Although young children have an increased propensity...
Retention of HIV-infected children in the first 12 months of anti-retroviral therapy and predictors of attrition in resource limited settings: A systematic review
Current UNAIDS goals aimed to end the AIDS epidemic set out to ensure that 90% of all people living with HIV know their status, 90% initiate and continue life-long anti-retroviral...
