Category Archives: Children or Youth (less than 18 years old)
Adolescent sexual and reproductive health services and implications for the provision of voluntary medical male circumcision: Results of a systematic literature review
BACKGROUND: Voluntary medical male circumcision (VMMC) is a critical HIV prevention tool. Since 2007, sub-Saharan African countries with the highest prevalence of HIV have been mobilizing resources to make VMMC...
Risk factors for respiratory syncytial virus associated with acute lower respiratory infection in children under five years: Systematic review and meta-analysis
BACKGROUND: Respiratory syncytial virus (RSV) is the most common pathogen identified in young children with acute lower respiratory infection (ALRI) as well as an important cause of hospital admission. The...
HIV orphanhood research and the representation of older orphans in Sub-Saharan Africa: A literature review
One impact of incurable HIV infection is the large number of orphans and vulnerable children (OVC) who are affected by HIV. The age-based criteria used to determine support eligibility for...
Prevalence of oral candidiasis in HIV/AIDS children in highly active antiretroviral therapy era. A literature analysis
SummaryHighly active antiretroviral therapy has decreased the morbidity and mortality related to HIV infection, including oral opportunistic infections. This paper offers an analysis of the scientific literature on the epidemiological...
The effectiveness of HIV/AIDS school-based sexual health education programmes in Nigeria: A systematic review
HIV/AIDS is one of the most important public health challenges facing Nigeria today. Recent evidence has revealed that the adolescent population make up a large proportion of the 3.7% reported...
Mapping the epidemiology of Kaposi Sarcoma and non-Hodgkin lymphoma among children in Sub-Saharan Africa: A review
Children with human immunodeficiency virus (HIV) have an increased risk of developing Kaposi Sarcoma (KS) and non-Hodgkin lymphoma (NHL) compared to HIV-negative children. We compiled currently published epidemiologic data on...
Mortality risk and associated factors in HIV-exposed, uninfected children
OBJECTIVE: With increasing maternal antiretroviral treatment (ART), the number of children newly infected with HIV has declined. However, the possible increased mortality in the large number of HIV-exposed, uninfected (HEU)...
Option B+ for the prevention of mother-to-child transmission of HIV infection in developing countries: A review of published cost-effectiveness analyses
OBJECTIVE: To review the published literature on the cost effectiveness of Option B+ (lifelong antiretroviral therapy) for preventing mother-to-child transmission (PMTCT) of HIV during pregnancy and breastfeeding to inform decision...
Incidence and prevalence of opportunistic and other infections and the impact of antiretroviral therapy among HIV-infected children in low and middle-income countries: A systematic review and meta-analysis
BACKGROUND: We conducted a systematic review and meta-analysis to evaluate the incidence and prevalence of 14 opportunistic infections (OIs) and other infections as well as the impact of antiretroviral therapy...
Adverse events associated with abacavir use in HIV-infected children and adolescents: A systematic review and meta-analysis
BACKGROUND: Concerns exist about the toxicity of drugs used in the implementation of large-scale antiretroviral programmes, and documentation of antiretroviral toxicity is essential. We did a systematic review and meta-analysis...
A synthesis of meta-analytic evidence of behavioral interventions to reduce HIV/STIs
To identify the mode of delivery, communicator, and content dimensions that make STI/HIV prevention interventions most successful at increasing condom use/protected sex or reducing STI/HIV incidence. A literature search for...
TB as a cause of hospitalization and in-hospital mortality among people living with HIV worldwide: A systematic review and meta-analysis
INTRODUCTION: Despite significant progress in improving access to antiretroviral therapy over the past decade, substantial numbers of people living with HIV (PLHIV) in all regions continue to experience severe illness...