Category Archives: Children or Youth (less than 18 years old)
Renal and bone adverse effects of a Tenofovir-based regimen in the treatment of HIV-infected children: A systematic review
INTRODUCTION: Tenofovir disoproxil fumarate (TDF)-containing regimens in the treatment of HIV-infected children have safety concerns with respect to renal and bone toxicity. OBJECTIVE: The aim of this study was to...
Optimal strategies for monitoring response to antiretroviral therapy in HIV-infected adults, adolescents, children and pregnant women: A systematic review
OBJECTIVE: The objective of this review was to examine different monitoring strategies (clinical, immunologic (CD4 T cell count measurement) and virologic (viral load measurement)) to inform revision of the 2013...
Service delivery interventions to improve adolescents’ linkage, retention and adherence to antiretroviral therapy and HIV care
OBJECTIVES: Adolescents living with HIV face substantial difficulties in accessing HIV care services and have worse treatment outcomes than other age groups. The objective of this review was to evaluate...
Uptake and yield of HIV testing and counselling among children and adolescents in sub-Saharan Africa: A systematic review
INTRODUCTION: In recent years children and adolescents have emerged as a priority for HIV prevention and care services. We conducted a systematic review to investigate the acceptability, yield and prevalence...
Adherence to antiretroviral therapy in adolescents living with HIV: Systematic review and meta-analysis
OBJECTIVE: Adolescent and young adult (AYA) populations (12-24 years) represent over 40% of new HIV infections globally. Adolescence is sometimes characterized by high-risk sexual behaviour and a lack of engagement...
Is dental caries experience increased in HIV-infected children and adolescents? A meta-analysis
OBJECTIVE: To undertake a systematic review to assess if HIV-infected children and adolescents have an increased dental caries experience. METHODS: A search of MEDLINE, BIREME, EMBASE, GOOGLE SCHOLAR, SIGLE (Grey...
Is the sexual behaviour of young people in sub-Saharan Africa influenced by their peers? A systematic review
Adolescents in sub-Saharan Africa are highly vulnerable to HIV, other sexually transmitted infections (STIs) and unintended pregnancies. Evidence for the effectiveness of individual behaviour change interventions in reducing incidence of...
Mitochondrial disorders among infants exposed to HIV and antiretroviral therapy
Although antiretroviral therapy (ART) is critical for preventing mother-to-child transmission of HIV, concern has been raised about the possibility that it may cause mitochondrial dysfunction in infants. There is adequate...
Child-rearing practices of primary caregivers of HIV-infected children: An integrative review of the literature
The number of human immunodeficiency virus (HIV)-infected children has increased because of the HIV and acquired immunodeficiency syndrome epidemic. Yet little is known about the child-rearing practices of these children’s...
