Category Archives: Children or Youth (less than 18 years old)

Uptake and yield of HIV testing and counselling among children and adolescents in sub-Saharan Africa: A systematic review

2015

INTRODUCTION: In recent years children and adolescents have emerged as a priority for HIV prevention and care services. We conducted a systematic review to investigate the acceptability, yield and prevalence...

Adherence to antiretroviral therapy in adolescents living with HIV: Systematic review and meta-analysis

2014

OBJECTIVE: Adolescent and young adult (AYA) populations (12-24 years) represent over 40% of new HIV infections globally. Adolescence is sometimes characterized by high-risk sexual behaviour and a lack of engagement...

Is dental caries experience increased in HIV-infected children and adolescents? A meta-analysis

2015

OBJECTIVE: To undertake a systematic review to assess if HIV-infected children and adolescents have an increased dental caries experience. METHODS: A search of MEDLINE, BIREME, EMBASE, GOOGLE SCHOLAR, SIGLE (Grey...

Is the sexual behaviour of young people in sub-Saharan Africa influenced by their peers? A systematic review

2015

Adolescents in sub-Saharan Africa are highly vulnerable to HIV, other sexually transmitted infections (STIs) and unintended pregnancies. Evidence for the effectiveness of individual behaviour change interventions in reducing incidence of...

Sexual risk reduction interventions for HIV prevention among South African youth: A meta-analytic review

2013

OBJECTIVES: To examine the efficacy of sexual risk reduction interventions among South African youth. METHODS: Electronic databases were searched to identify studies published between 2007 and early 2013. Studies were...

Review: An urgent need for research on factors impacting adherence to and retention in care among HIV-positive youth and adolescents from key populations

2014

INTRODUCTION: The 50% increase in HIV-related deaths in youth and adolescents (aged 10-24) from 2005 to 2012 highlights the need to improve HIV treatment and care in this population, including...

Viral suppression in adolescents on antiretroviral treatment: Review of the literature and critical appraisal of methodological challenges

2016

OBJECTIVE: Medication adherence is often sub-optimal for adolescents with HIV, and establishing correct weight-based antiretroviral therapy dosing is difficult, contributing to virological failure. This review aimed to determine the proportion...

Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

2005

BACKGROUND: Mother-to-child transmission (MTCT) of HIV is the dominant mode of acquisition of HIV infection for children, currently resulting in more than 2000 new paediatric HIV infections each day worldwide....

Antiretroviral interventions for preventing breast milk transmission of HIV

2014

BACKGROUND: An estimated 260,000 children under the age of 15 years acquired HIV infection in 2012. As much as 42% of mother-to-child transmission is related to breastfeeding. Antiretroviral prophylaxis for...

Conjugated heptavalent pneumococcal vaccine

2002

OBJECTIVE: To review the immunogenicity, efficacy, and safety of the heptavalent conjugated pneumococcal vaccine (PCV7). DATA SOURCES: A MEDLINE search (1993–August 2001) of research limited to humans published in the...

Effective approaches to reducing adolescent unprotected sex, pregnancy, and childbearing

2002

In the United States, there exist a multitude of different approaches to reducing adolescent sexual risk-taking, unintended pregnancy, childbearing, and sexually transmitted disease, including HIV. While many of these approaches...

Optimization of antiretroviral therapy in HIV-infected children under 3 years of age: A systematic review

2014

BACKGROUND: In the absence of antiretroviral therapy (ART), over 50% of HIV-infected infants progress to AIDS and death by 2 years of age. However, there are challenges to initiation of...

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