Category Archives: Children or Youth (less than 18 years old)
Determinants of HIV related mortality in African children on antiretroviral therapy: Clinical and immunological insights from a systematic review and meta-analysis
BACKGROUND: The HIV epidemic in Africa is still a serious public health concern, particularly for children who are more vulnerable to its negative consequences. Various studies carried out in different...
Prevalence and factors influencing HIV testing behavior in adolescents and young adults: A systematic review and meta-analysis
Objective To systematically evaluate the prevalence and influencing factors of human immunodeficiency virus (HIV) testing among adolescents and young adults (10–25 years old), providing a reference for optimizing testing strategies and...
Probability of vertical HIV transmission: A systematic review and meta-regression
Background Eliminating HIV vertical transmission is a global priority and monitored by estimating paediatric HIV infections with the UNAIDS-supported Spectrum AIDS Impact Module (Spectrum-AIM). Recent innovations in antiretroviral therapy (ART)...
Single-session interventions to enhance HIV outcomes among adolescents and young adults: A systematic scoping review and implications for integrating HIV and mental health services
Significant progress has been made in HIV prevention and treatment for adolescents and young adults (AYA), but integrating mental healthcare remains essential to address risks and improve treatment engagement. Single-session...
HIV-related mortality time trends among children and young adolescents on antiretroviral therapy by age, treatment duration, and region: A systematic review and meta-regression analysis
Background: Past cohort studies have examined mortality among children and young adolescents (aged 0–14 years) who have received antiretroviral therapy (ART), but no systematic reviews have been undertaken to synthesise these...
Cost-effectiveness analyses of adolescent- and young-adult-focused HIV interventions incorporating HIV transmission: A scoping review of modeling methods and proposed guidance
BACKGROUND: Adolescents and young adults (AYA) are disproportionately affected by human immunodeficiency virus (HIV) globally, with high-burden population subgroups differing across regions. Cost-effectiveness modeling analyses of AYA-focused HIV interventions have...
Risk perception of human immunodeficiency virus, acquired immune deficiency syndrome, and reproductive health education among among junior and senior high school students: A scoping review
This scoping review aims to identify studies that examine the existence and impact of HIV/AIDs education among high school-aged individuals in Ghana, underscoring the association of factors such as stigma...
Mobile health intervention tools promoting HIV pre-exposure prophylaxis among adolescent girls and young women in sub-Saharan Africa: Scoping review
BACKGROUND: In 2022, 3100 adolescent girls and young women in sub-Saharan Africa experienced new HIV infections each week. HIV pre-exposure prophylaxis (PrEP) is effective at preventing HIV but has limited...
Incidence and predictors of mortality among children with severe acute malnutrition admitted to therapeutic feeding units in Ethiopia: A systematic review and meta-analysis
Objective To estimate the mortality rate and identify predictors of mortality among under-five children with severe acute malnutrition (SAM) admitted to therapeutic feeding units (TFUs) in Ethiopia. Methods We searched...
Magnitude and characteristics of unsuppressed HIV viral load in children and adolescents on antiretroviral therapy in sub-Saharan Africa: A systematic review and meta-analysis
Background: HIV/AIDS remains a major health issue in sub-Saharan Africa, especially among children and adolescents, with a substantial proportion of people with HIV having unsuppressed viral loads despite the availability of...
Mental health interventions for young pepole living with HIV/AIDS in sub-Saharan Africa: A systematic review
Introduction: Young people (aged 15-24) living with HIV/AIDS (YPLHIV) in sub-Saharan Africa (SSA) experience higher rates of mental health conditions compared to their uninfected peers. Research and practitioners have expressed...
Transition From adolescent to adult care for young people living with HIV: A systematic review of needs, barriers, and interventions
Young people living with HIV (YPLHIV) aged 15-24 years represent over 25% of new HIV infections globally. They face significant challenges in transitioning from pediatric to adult care. Despite guidelines...
