Category Archives: Children or Youth (less than 18 years old)
Duration of ruptured membranes and vertical transmission of HIV-1: A meta-analysis from 15 prospective cohort studies
Objective: To test the a priori hypothesis that longer duration of ruptured membranes is associated with increased risk of vertical transmission of HIV. Design: The relationship between duration of ruptured...
Association between knowledge of HIV-positive status or use of antiretroviral therapy and high-risk transmission behaviors: Systematic review
To systematically review the evidence on the association between knowledge of HIV-positive status or use of antiretroviral therapy (ART) and high-risk transmission behaviors, we searched Ovid MEDLINE from 2004 to...
The paradigm of universal access to HIV-treatment and human rights violation: How do we treat HIV-positive people who use drugs?
HIV-positive people who use drugs (PWUDs) are particularly vulnerable for suboptimal access to highly active antiretroviral therapy (HAART). We conducted a systematic review to identify factors associated with suboptimal HAART...
Retention in care of HIV-infected children from HIV test to start of antiretroviral therapy: Systematic review
BACKGROUND: In adults it is well documented that there are substantial losses to the programme between HIV testing and start of antiretroviral therapy (ART). The magnitude and reasons for loss...
HIV prevention for South African youth: which interventions work? A systematic review of current evidence
BACKGROUND: In South Africa, HIV prevalence among youth aged 15-24 is among the world’s highest. Given the urgent need to identify effective HIV prevention approaches, this review assesses the evidence...
Efficacy of interventions in improving highly active antiretroviral therapy adherence and HIV-1 RNA viral load: A meta-analytic review of randomized controlled trials
Summary: Adherence to highly active antiretroviral therapy (HAART) is generally suboptimal, limiting the effectiveness of HAART. This meta-analytic review examined whether behavioral interventions addressing HAART adherence are successful in increasing...
Efficacy of computer technology-based HIV prevention interventions: A meta-analysis
OBJECTIVES: To conduct a meta-analysis of computer technology-based HIV prevention behavioral interventions aimed at increasing condom use among a variety of at-risk populations. DESIGN: Systematic review and meta-analysis of existing...
Sexual health education interventions for young people: A methodological review
Objectives: To locate reports of sexual health education interventions for young people, assess the methodological quality of evaluations, identify the subgroup with a methodologically sound design, and assess the evidence...
Systematic review of abstinence-plus HIV prevention programs in high-income countries
BACKGROUND: Abstinence-plus (comprehensive) interventions promote sexual abstinence as the best means of preventing HIV, but also encourage condom use and other safer-sex practices. Some critics of abstinence-plus programs have suggested...
Treatment for leiomyosarcoma and leiomyoma in children with HIV infection
BACKGROUND: Smooth muscle tumour (SMT) composed of leiomyoma and leiomyosarcoma recently has been described in many HIV-infected children. Leiomyosarcoma has become the second most frequent malignancy in children with HIV...
